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Anti-PSGL-1/CD162 Antibody (3U936)

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产品编号 TMAY-03455

Anti-PSGL-1/CD162 Antibody (3U936) 是一种 Rabbit 抗体,靶向 PSGL-1/CD162。Anti-PSGL-1/CD162 Antibody (3U936) 可用于 FCM。

Anti-PSGL-1/CD162 Antibody (3U936)

Anti-PSGL-1/CD162 Antibody (3U936)

Rating icon 还可以
产品编号 TMAY-03455

Anti-PSGL-1/CD162 Antibody (3U936) 是一种 Rabbit 抗体,靶向 PSGL-1/CD162。Anti-PSGL-1/CD162 Antibody (3U936) 可用于 FCM。

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产品介绍

生物活性
产品描述
Anti-PSGL-1/CD162 Antibody (3U936) is a Rabbit antibody targeting PSGL-1/CD162. Anti-PSGL-1/CD162 Antibody (3U936) can be used in FCM.
Ig Type
Monoclonal Rabbit IgG
克隆号
3U936
交叉反应
Mouse
验证活性
Flow cytometric analysis of Mouse SELPLG(CD162) expression on BABL/c splenocytes. Cells were stained with purified anti-Mouse SELPLG(CD162), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
应用
FCM
推荐剂量
FCM: 1:25-1:100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse PSGL-1/CD162 (rM PSGL-1/CD162; TMPY-03354; Q62170; Met1-Cys307).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景P-selectin glycoprotein ligand-1 (PSGL-1), also known as SELPLG or CD162, is the high affinity ounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. PSGL-1 is a mucin-type glycoprotein, expressed on leukocytes and platelets as a homodimer of two disulfide-linked subunits of ~12 kD. As cell adhesion molecules, multiple studies have shown that PSGL-1/ P-selectin interaction is required for the normal recruitment of leukocytes during inflammatory reactions, and also participates in hemostatic responses. PSGL-1 protein requires two distinct posttranslational modifications for the Ca2+-dependent recognition by the lectin domain of P-selectin, that is tyrosine sulfation and specific O-linked glycosylation (sialic acid and fucose). PSGL-1 can also bind to other two members of the selectin family, E-selectin (endothelial) and L-selectin (leukocyte), but binds best to P-selectin.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
APC/FITC/PE
可提供抗体种类
4
抗原信息
免疫原
Recombinant Mouse PSGL-1/CD162 Protein (TMPY-03354)
抗原种属
Mouse
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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4个月前
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