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IL-18BP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated

Synonyms: Interleukin-18-binding protein, IL-18BP, Igifbp
货号 TMPK-00492 一键复制产品信息
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SPR兼容缓冲液

Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggesting that IL-18 therapy could enhance anti-tumour immunity. IL-18BP, a high-affinity IL-18 decoy receptor, is frequently upregulated in diverse human and mouse tumours and limits the anti-tumour activity of IL-18 in mice. IL-18BP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 21.14 kDa and the accession number is A0A2K5UDJ4.

IL-18BP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated

一键复制产品信息
Rating icon 还可以
SPR兼容缓冲液
货号 TMPK-00492

别名 Interleukin-18-binding protein, IL-18BP, Igifbp

Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggesting that IL-18 therapy could enhance anti-tumour immunity. IL-18BP, a high-affinity IL-18 decoy receptor, is frequently upregulated in diverse human and mouse tumours and limits the anti-tumour activity of IL-18 in mice. IL-18BP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 21.14 kDa and the accession number is A0A2K5UDJ4.

IL-18BP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
其他形式的 “IL-18BP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated”:
IL-18BPd Protein, Mouse, Recombinant (hFc)
IL-18BP Protein, Human, Recombinant (hFc)
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规格价格库存数量
5 μg
¥ 568
6-8日内发货
10 μg
¥ 928
6-8日内发货
20 μg
¥ 1,530
5日内发货
50 μg
¥ 2,970
5日内发货
100 μg
¥ 5,180
5日内发货
200 μg
¥ 9,390
5日内发货
500 μg
¥ 20,700
5日内发货
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产品介绍

生物活性
产品描述
Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggesting that IL-18 therapy could enhance anti-tumour immunity. IL-18BP, a high-affinity IL-18 decoy receptor, is frequently upregulated in diverse human and mouse tumours and limits the anti-tumour activity of IL-18 in mice. IL-18BP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 21.14 kDa and the accession number is A0A2K5UDJ4.
生物活性
Biotinylated Cynomolgus IL-18BP, His tag captured on CM5 Chip via anti-his antibody can bind Human IL-18, No Tag with an affinity constant of 1.67 nM as determined in SPR assay.
研究背景
Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggesting that IL-18 therapy could enhance anti-tumour immunity. IL-18BP, a high-affinity IL-18 decoy receptor, is frequently upregulated in diverse human and mouse tumours and limits the anti-tumour activity of IL-18 in mice.
种属
Cynomolgus
表达系统
HEK293 Cells
标签
C-His
蛋白编号A0A2K5UDJ4
蛋白构建
Thr28-Pro207
蛋白纯度
> 95% as determined by Tris-Bis PAGE; > 90% as determined by HPLC
蛋白性状
Solution
缓冲液
Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
别名
Interleukin-18-binding protein, IL-18BP, Igifbp
内毒素< 1.0 EU/μg of the protein as determined by the LAL method.
化学信息
分子量21.14 kDa (predicted). Due to glycosylation, the protein migrates to 50-65 kDa based on Tris-Bis PAGE result.
储存&溶解度
运输方式In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
存储

It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

计算器

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剂量转换

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技术支持

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