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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Endostatin Polyclonal Antibody

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货号 TMAB-00610

别名 type XVIII, Endostatin, collagen α-1(XVIII)chain, collagen alpha-1(XVIII)chain, collagen, COL18A1, antiangiogenic agent

Anti-Endostatin Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Endostatin。Anti-Endostatin Polyclonal Antibody 可用于 IF,IHC-Fr,WB。

Anti-Endostatin Polyclonal Antibody

Anti-Endostatin Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-00610 别名 type XVIII, Endostatin, collagen α-1(XVIII)chain, collagen alpha-1(XVIII)chain, collagen, COL18A1, antiangiogenic agent

Anti-Endostatin Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Endostatin。Anti-Endostatin Polyclonal Antibody 可用于 IF,IHC-Fr,WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-Endostatin Polyclonal Antibody is a Rabbit antibody targeting Endostatin. Anti-Endostatin Polyclonal Antibody can be used in IF,IHC-Fr,WB.
别名type XVIII, Endostatin, collagen α-1(XVIII)chain, collagen alpha-1(XVIII)chain, collagen, COL18A1, antiangiogenic agent
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat)
验证活性
Sample:
Liver (Mouse) Lysate at 40 μg
Primary: Anti-Endostatin (TMAB-00610) at 1/500 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 20/190 kDa
Observed band size: 155 kDa
verifiedActivity
应用IFIHC-FrWB
推荐剂量
WB: 1:500-2000; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted, extracellular space, extracellular matrix.
组织特异性Present in multiple organs with highest levels in liver, lung and kidney.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Two transcript variants encoding different isoforms have been found for this gene.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Endostatin
抗原种属
Human
基因名称
COL18A1
基因ID
80781
蛋白名称
Collagen alpha-1(XVIII) chain
Uniprot ID
P39060
研究领域
Angiogenic inhibitory factors,Inhibitors,Collagen
功能
COLA18A probably plays a major role in determining the retinal structure as well as in the closure of the neural tube.
Endostatin potently inhibits endothelial cell proliferation and angiogenesis. May inhibit angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling.
化学信息
分子量Theoretical: 20/190 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

计算器

  • 稀释 计算器

关键词

collagen a-1(XVIII)chain
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