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别名 抗小鼠ICOSL/CD275 抗体 (HK5.3)
Anti-Mouse ICOSL/CD275 Antibody (HK5.3) 是抗小鼠 ICOSL/CD275 的单克隆抗体,可抑制 T 细胞与内皮细胞的黏附,减少 TR Treg 细胞的扩增,适用于流感病毒感染、关节炎等炎症与感染性疾病的相关研究。
Anti-Mouse ICOSL/CD275 Antibody (HK5.3) 是抗小鼠 ICOSL/CD275 的单克隆抗体,可抑制 T 细胞与内皮细胞的黏附,减少 TR Treg 细胞的扩增,适用于流感病毒感染、关节炎等炎症与感染性疾病的相关研究。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 1 mg | ¥ 446 | 4-6周 | |
| 5 mg | ¥ 1,870 | 4-6周 | |
| 10 mg | 待询 | 4-6周 |
| 产品描述 | Anti-Mouse ICOSL/CD275 Antibody (HK5.3) is a monoclonal antibody against mouse ICOSL/CD275. It inhibits the adhesion between T cells and endothelial cells, reduces the expansion of TR Treg cells, and is suitable for studies on inflammatory and infectious diseases such as influenza virus infection and arthritis. |
| 体外活性 | Anti-Mouse ICOSL/CD275 Antibody (HK5.3)(15 μg/mL,30 分钟处理)可显著降低 Th1、Th17 细胞与原代小鼠脑微血管内皮细胞(pMBMECs)的黏附水平 [2]。 |
| 体内活性 | Anti-Mouse ICOSL/CD275 Antibody (HK5.3)(100 μg,腹腔注射,于流体动力学尾静脉注射后第 0、3、6、9 天给药)可显著降低肝细胞衰老模型野生型 C57BL/6 小鼠体内衰老肝细胞的清除效率 [1]。 |
| 别名 | 抗小鼠ICOSL/CD275 抗体 (HK5.3) |
| 克隆号 | HK5.3 |
| 反应种属 | Mouse |
| 应用 | ELISA FCM Functional assay |
| 抗体种类 | Monoclonal |
| 缓冲液 | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| 内毒素 | <1.0 EU/mg |
| 同型 | Rat IgG2a kappa |
| 推荐同型对照 |
| 偶联 | Unconjugated |
| 基因ID | |
| Uniprot ID | |
| 靶点 | ICOSL/CD275 |
| 分子量 | 150 kDa |
| 存储 | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
对于不同动物的给药剂量换算,您也可以参考 更多