SIRP gamma Protein, Human, Recombinant (His & Avi)

Signal regulatory protein gamma (SIRP gamma, designated CD172g), also called SIRP beta 2, is a monomeric 45-47 kDa type I transmembrane protein belonging to the SIRP/SHPS (CD172) family of the Ig superfamily.SIRP gamma is probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. SIRP gamma Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 39.7 kDa and the accession number is Q9P1W8.

规格	价格/CNY		数量
100 μg	￥ 2,210	5日内发货
500 μg	￥ 8,900	5日内发货
1 mg	￥ 14,800	5日内发货

规格

价格/CNY

货期

数量

100 μg

￥ 2,210

5日内发货

500 μg

￥ 8,900

5日内发货

1 mg

￥ 14,800

5日内发货

生物活性

Immobilized Human SIRP Gamma, His Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Human CD47, hFc Tag with the EC50 of 2.46μg/ml determined by ELISA.

产品描述

种属	Human
表达系统	HEK293 Cells
标签	C-His-Avi
蛋白编号	Q9P1W8
别名	SIRP-B2, bA77C3.1, CD172g, SIRP β 2, SIRP gamma, SIRP beta 2, SIRP γ, FLJ42230, SIRP β2, Cripto-1, SIRPG, SIRP γ/CD172g
蛋白构建	Glu29-Pro360
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量	39.7 kDa (predicted). Due to glycosylation, the protein migrates to 45-52 kDa based on Tris-Bis PAGE result.

内毒素	< 1 EU/μg by the LAL method.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	Signal regulatory protein gamma (SIRP gamma, designated CD172g), also called SIRP beta 2, is a monomeric 45-47 kDa type I transmembrane protein belonging to the SIRP/SHPS (CD172) family of the Ig superfamily.SIRP gamma is probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation.