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Anti-FOXP3 Antibody (3C391)
还可以产品编号 TMAY-01587
Anti-FOXP3 Antibody (3C391) 是一种 Mouse 抗体，靶向 FOXP3。Anti-FOXP3 Antibody (3C391) 可用于 IHC-P。
Anti-FOXP3 Antibody (3C391)
Anti-FOXP3 Antibody (3C391)
还可以产品编号 TMAY-01587
Anti-FOXP3 Antibody (3C391) 是一种 Mouse 抗体，靶向 FOXP3。Anti-FOXP3 Antibody (3C391) 可用于 IHC-P。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-FOXP3 Antibody (3C391) is a Mouse antibody targeting FOXP3. Anti-FOXP3 Antibody (3C391) can be used in IHC-P. |
| Ig Type | Monoclonal mouse IgG2a |
| 克隆号 | 3C391 |
| 交叉反应 | Human |
| 验证活性 | 1. Immunochemical staining of human FOXP3 in human carcinoma of sigmoid with mouse monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections. 2. Immunochemical staining of human FOXP3 in human breast carcinoma with mouse monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections. |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:100-1:500 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, a synthetic peptide corresponding to the center region of the human FOXP3. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS with 10% Trehalose, 0.02% Tween 80, pH7.0 |
| 研究背景 | Forkhead box P3 (FOXP3) is a key gene in the immune system which also plays a role in tumor development. The Treg cell lineage-specification factor FOXP3 (forkhead box P3) is essential for Treg cells' ability to uphold immunologic tolerance. Forkhead box protein 3 (FOXP3) is expressed in numerous types of tumor cell and is associated with tumor progression and prognosis. which had been reported that FOXP3 inhibited cellular proliferation and induced apoptosis of gastric cancer (GC) cells by activating the apoptosis signaling pathway. The elevated expression of FOXP3 in blood and urine samples from kidney transplant recipients could be a useful noninvasive biomarker to diagnose graft dysfunction. Forkhead box P3 (FOXP3), an X-linked tumor suppressor gene, plays an important role in breast cancer. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide corresponding to the center region of the Human FOXP3 |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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