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Anti-FSCN1 Antibody (7Z181) 是一种 Rabbit 抗体,靶向 FSCN1。Anti-FSCN1 Antibody (7Z181) 可用于 WB,ICC/IF,IHC,IP,FCM。
Anti-FSCN1 Antibody (7Z181) 是一种 Rabbit 抗体,靶向 FSCN1。Anti-FSCN1 Antibody (7Z181) 可用于 WB,ICC/IF,IHC,IP,FCM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,485 | 5日内发货 | |
100 μL | ¥ 2,485 | 5日内发货 |
产品描述 | Anti-FSCN1 Antibody (7Z181) is a Rabbit antibody targeting FSCN1. Anti-FSCN1 Antibody (7Z181) can be used in WB,ICC/IF,IHC,IP,FCM. |
别名 | Strongylocentrotus purpuratus, SNL, Singed drosophila homolog like, Singed (Drosophila) like (sea urchin fascin homolog like), Singed, sea urchin, p55, HSN, FSCN 1, FLJ38511, Fascin1, Fascin homolog 1 actin bundling protein, Fascin homolog 1, Fascin actin bundling protein 1, Fascin 1, Fascin, FAN1, FAN 1, 55 kDa actin-bundling protein, 55 kDa actin bundling protein |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of Fascin on different lysates using anti-Fascin antibody at 1/1,000 dilution. Positive control: Lane1: SH-SY5Y, Lane2: Human brain, Lane3: Rat spleen, Lane4: Mouse testes, Lane5: Mouse brain, Lane6: Mouse spleen. 2. Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-Fascin antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Fascin antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Fascin antibody. Counter stained with hematoxylin. 5. ICC staining Fascin in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 6. ICC staining Fascin in SW480 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 7. ICC staining Fascin in SH-SY5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 8. Flow cytometric analysis of Hela cells with Fascin antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). |
应用 | |
推荐剂量 | WB: 1:500-1000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Cell adhesion to extracellular matrix is an important physiological stimulus for organization of the Actin-based cytoskeleton. Adhesion to the matrix glycoprotein Thrombospondin 1 triggers the sustained formation of F-Actin microspikes that contain the Actin-bundling protein Fascin. These structures are also implicated in cell migration, which may be an important function of Thrombospondin 1 in tissue remodelling and wound repair. Fascin bundles Actin microfilaments within dynamic cellular structures such as microspikes, stress fibers and membrane ruffles. Fascin could serve as a prognostic factor for abnormal ovarian epithelial pathology and could be a novel target for the treatment of ovarian cancer. Fascin, an Actin-bundling protein, identifies dendritic cells in the blood and in tissues. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 54 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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