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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CYP3A4 Antibody (8Y208)

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货号 TMAB-04897

Anti-CYP3A4 Antibody (8Y208) 是一种 Rabbit 抗体，靶向 CYP3A4。Anti-CYP3A4 Antibody (8Y208) 可用于 WB,IHC-P,IHC-Fr,IP,IF。

Anti-CYP3A4 Antibody (8Y208)

Anti-CYP3A4 Antibody (8Y208)

一键复制产品信息
Rating icon 还可以
货号 TMAB-04897

Anti-CYP3A4 Antibody (8Y208) 是一种 Rabbit 抗体，靶向 CYP3A4。Anti-CYP3A4 Antibody (8Y208) 可用于 WB,IHC-P,IHC-Fr,IP,IF。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-CYP3A4 Antibody (8Y208) is a Rabbit antibody targeting CYP3A4. Anti-CYP3A4 Antibody (8Y208) can be used in WB,IHC-P,IHC-Fr,IP,IF.
Ig Type
IgG
克隆号
8Y208
反应种属
Human
应用WBIHC-PIHC-FrIPIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IP: 1:20-50; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Endoplasmic reticulum, membrane bound.
组织特异性Expressed in prostate and liver. According to some authors, it is not expressed in brain (PubMed:19094056). According to others, weak levels of expression are measured in some brain locations (PubMed:19359404 and PubMed:18545703). Also expressed in epithelium of the small intestine and large intestine, bile duct, nasal mucosa, kidney, adrenal cortex, epithelium of the gastric mucosa with intestinal metaplasia, gallbladder, intercalated ducts of the pancreas, chief cells of the parathyroid and the corpus luteum of the ovary (at protein level).
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景A cytochrome P450 monooxygenase involved in the metabolism of sterols, steroid hormones, retinoids and fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds.
抗原信息
免疫原
A synthesized peptide: human Cytochrome P450 3A4
抗原种属
Human
基因名称
CYP3A4
基因ID
1576
蛋白名称
Cytochrome P450 3A4
Uniprot ID
P08684
功能
In animals, P-450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs. The four major families involved in drug metabolism are CYP 1,2,3, and 4. Cytochrome P450 3A4 [human-3A1 Rat] is abundantly expressed in liver and small intestine and is inducible by barbiturates, glucocorticoids and rifampicin.
化学信息
分子量Theoretical: 57 kDa. Actual: 57 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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