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顶部生物活性储存和溶解信息计算器

Anti-Phospho-PLK1 (Ser137) Polyclonal Antibody

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Anti-Phospho-PLK1 (Ser137) Polyclonal Antibody
产品编号 TMAC-03384
别名 p-PLK1 (Ser137), p-PLK1 (S137), PLK1 (p-Ser137), PLK1 (p-S137)

Anti-Phospho-PLK1 (Ser137) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-PLK1 (Ser137)。Anti-Phospho-PLK1 (Ser137) Polyclonal Antibody 可用于 WB。

Anti-Phospho-PLK1 (Ser137) Polyclonal Antibody

Anti-Phospho-PLK1 (Ser137) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-PLK1 (Ser137) Polyclonal Antibody
产品编号 TMAC-03384 别名 p-PLK1 (Ser137), p-PLK1 (S137), PLK1 (p-Ser137), PLK1 (p-S137)

Anti-Phospho-PLK1 (Ser137) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-PLK1 (Ser137)。Anti-Phospho-PLK1 (Ser137) Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,245
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-PLK1 (Ser137) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PLK1 (Ser137). Anti-Phospho-PLK1 (Ser137) Polyclonal Antibody can be used in WB.
别名p-PLK1 (Ser137), p-PLK1 (S137), PLK1 (p-Ser137), PLK1 (p-S137)
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of extracts from Jurkat cells treated with PMA, using PLK1 (Phospho-Ser137) antibody TMAC-03384. The lane on the right is treated with the synthesized peptide.
应用
WB
推荐剂量
WB: 1:500-3000
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of anaphase-promoting complex/cyclosome (APC/C) inhibitors, and the regulation of mitotic exit and cytokinesis. Polo-like kinase proteins acts by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains. Phosphorylates BORA, BUB1B/BUBR1, CCNB1, CDC25C, CEP55, ECT2, ERCC6L, FBXO5/EMI1, FOXM1, KIF20A/MKLP2, CENPU, NEDD1, NINL, NPM1, NUDC, PKMYT1/MYT1, KIZ, PPP1R12A/MYPT1, PRC1, RACGAP1/CYK4, SGOL1, STAG2/SA2, TEX14, TOPORS, p73/TP73, TPT1 and WEE1. Plays a key role in centrosome functions and the assembly of bipolar spindles by phosphorylating KIZ, NEDD1 and NINL.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of serine 137 (R-R-S(p)-L-L) derived from Human PLK1
抗原种属
human
Uniprot ID
P53350
化学信息
分子量Actual: 68 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

pPLK1 (Ser137)pPLK1 (S137)PLK1 (pSer137)PLK1 (pS137)PLK1 (phospho-Ser137)PLK1 (phospho-S137)

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