Name: CD96 Protein, Human, Recombinant (His & Avi), Biotinylated
Brand: TargetMol
SKU: TMPK-00875
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 568

6-8日内发货

10 μg

¥ 928

6-8日内发货

20 μg

¥ 1,530

5日内发货

50 μg

¥ 2,970

5日内发货

100 μg

¥ 5,180

5日内发货

200 μg

¥ 9,390

5日内发货

500 μg

¥ 20,700

5日内发货

生物活性

产品描述	The receptors CD96 and TIGIT are expressed on the surface of T and natural killer (NK) cells, and recent studies suggest both play important inhibitory roles in immune function. CD96 has been shown to modulate immune cell activity in mice, with Cd96-/- mice displaying hypersensitive NK-cell responses to immune challenge and significant tumor resistance. The counterbalance between the putative inhibitory CD96 and TIGIT receptors and the activating receptor, CD226, offers unique strategies for immuno-oncology drug development.
生物活性	Immobilized Anti-CD96 Antibody, hFc Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human CD96, His Tag with the EC50 of 0.46μg/ml determined by ELISA.
研究背景	The receptors CD96 and TIGIT are expressed on the surface of T and natural killer (NK) cells, and recent studies suggest both play important inhibitory roles in immune function. CD96 has been shown to modulate immune cell activity in mice, with Cd96-/- mice displaying hypersensitive NK-cell responses to immune challenge and significant tumor resistance. The counterbalance between the putative inhibitory CD96 and TIGIT receptors and the activating receptor, CD226, offers unique strategies for immuno-oncology drug development.
种属	Human
表达系统	HEK293 Cells
标签	C-His-Avi
蛋白编号	P40200-2
蛋白构建	Val22-Met503
蛋白纯度	> 95% as determined by Tris-Bis PAGE
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	TACTILE, DKFZp667E2122, CD96 molecule, CD96
内毒素	< 1 EU/μg by the LAL method.

化学信息

分子量	59.1 kDa (predicted). Due to glycosylation, the protein migrates to 115-140 kDa based on Tris-Bis PAGE result.

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

CD96 Protein, Human, Recombinant (His & Avi), Biotinylated

CD96 Protein, Human, Recombinant (His & Avi), Biotinylated

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