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Anti-CD6 Antibody (2W437)

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Anti-CD6 Antibody (2W437)
产品编号 TMAY-03425
别名 TP120, CD6 molecule

Anti-CD6 Antibody (2W437) 是一种 Rabbit 抗体,靶向 CD6。Anti-CD6 Antibody (2W437) 可用于 ELISA,ELISA(Cap)。

Anti-CD6 Antibody (2W437)
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Anti-CD6 Antibody (2W437)

Rating icon 还可以
Anti-CD6 Antibody (2W437)
产品编号 TMAY-03425 别名 TP120, CD6 molecule

Anti-CD6 Antibody (2W437) 是一种 Rabbit 抗体,靶向 CD6。Anti-CD6 Antibody (2W437) 可用于 ELISA,ELISA(Cap)。

规格价格库存数量
20 μL
¥ 785
5日内发货
100 μL
¥ 2,279
5日内发货
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产品介绍

生物活性
产品描述
Anti-CD6 Antibody (2W437) is a Rabbit antibody targeting CD6. Anti-CD6 Antibody (2W437) can be used in ELISA,ELISA(Cap).
别名TP120, CD6 molecule
Ig Type
Rabbit IgG
克隆号
2W437
交叉反应
Mouse
应用
ELISA,ELISA(Cap)
推荐剂量
ELISA: 1:5000-1:10000; ELISA(Cap): 1:250-1:2000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD6 (rM CD6; TMPY-02254; Q91WN5; Met1-Gly396).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景T-cell differentiation antigen CD6, also known as TP12 and CD6, is a single-pass type I membrane protein which contains threeSRCR domains. CD6 / TP12 is a cell surface glycoprotein expressed primarily on T cells, it may function as a costimulatory molecule and may play a role in autoreactive immune responses. CD6 / TP12 is expressed by thymocytes, mature T-cells, a subset of B-cells known as B-1 cells, and by some cells in the brain. CD6 ligand termed CD166 (previously known as activated leukocyte cell adhesion molecule, ALCAM ) has been identified and shown to be expressed on activated T cells, B cells, thymic epithelium, keratinocytes, and in rheumatoid arthritis synovial tissue. CD6 / TP12 binds to activated leukocyte cell adhesion molecule ( CD166 ), and is considered as a costimulatory molecule involved in lymphocyte activation and thymocyte development. CD6 / TP12 partially associates with the TCR / CD3 complex and colocalizes with it at the center of the mature immunological synapse (IS) on T lymphocytes. During thymic development CD6-dependent signals may contribute both to thymocyte survival, and to the overall functional avidity of selection in both man and mouse.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Mouse CD6 protein (TMPY-02254)
抗原种属
Mouse
研究领域
ITIM/ITAM Immunoreceptors and Related Molecules
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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