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Anti-CD6 Antibody (2W437) 是一种 Rabbit 抗体,靶向 CD6。Anti-CD6 Antibody (2W437) 可用于 ELISA,ELISA(Cap)。
Anti-CD6 Antibody (2W437) 是一种 Rabbit 抗体,靶向 CD6。Anti-CD6 Antibody (2W437) 可用于 ELISA,ELISA(Cap)。
产品描述 | Anti-CD6 Antibody (2W437) is a Rabbit antibody targeting CD6. Anti-CD6 Antibody (2W437) can be used in ELISA,ELISA(Cap). |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 2W437 |
交叉反应 | Mouse |
应用 | ELISA,ELISA(Cap) |
推荐剂量 | ELISA: 1:5000-1:10000; ELISA(Cap): 1:250-1:2000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD6 (rM CD6; TMPY-02254; Q91WN5; Met1-Gly396). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | T-cell differentiation antigen CD6, also known as TP12 and CD6, is a single-pass type I membrane protein which contains threeSRCR domains. CD6 / TP12 is a cell surface glycoprotein expressed primarily on T cells, it may function as a costimulatory molecule and may play a role in autoreactive immune responses. CD6 / TP12 is expressed by thymocytes, mature T-cells, a subset of B-cells known as B-1 cells, and by some cells in the brain. CD6 ligand termed CD166 (previously known as activated leukocyte cell adhesion molecule, ALCAM ) has been identified and shown to be expressed on activated T cells, B cells, thymic epithelium, keratinocytes, and in rheumatoid arthritis synovial tissue. CD6 / TP12 binds to activated leukocyte cell adhesion molecule ( CD166 ), and is considered as a costimulatory molecule involved in lymphocyte activation and thymocyte development. CD6 / TP12 partially associates with the TCR / CD3 complex and colocalizes with it at the center of the mature immunological synapse (IS) on T lymphocytes. During thymic development CD6-dependent signals may contribute both to thymocyte survival, and to the overall functional avidity of selection in both man and mouse. |
偶联 | Unconjugated |
免疫原 | Recombinant Mouse CD6 protein (TMPY-02254) |
抗原种属 | Mouse |
研究领域 | ITIM/ITAM Immunoreceptors and Related Molecules |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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