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Anti-CD6 Antibody (2W437)

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产品编号 TMAY-03425

Anti-CD6 Antibody (2W437) 是一种 Rabbit 抗体,靶向 CD6。Anti-CD6 Antibody (2W437) 可用于 ELISA,ELISA(Cap)。

Anti-CD6 Antibody (2W437)

Anti-CD6 Antibody (2W437)

Rating icon 还可以
产品编号 TMAY-03425

Anti-CD6 Antibody (2W437) 是一种 Rabbit 抗体,靶向 CD6。Anti-CD6 Antibody (2W437) 可用于 ELISA,ELISA(Cap)。

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产品介绍

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产品描述
Anti-CD6 Antibody (2W437) is a Rabbit antibody targeting CD6. Anti-CD6 Antibody (2W437) can be used in ELISA,ELISA(Cap).
Ig Type
Monoclonal Rabbit IgG
克隆号
2W437
交叉反应
Mouse
应用
ELISA,ELISA(Cap)
推荐剂量
ELISA: 1:5000-1:10000; ELISA(Cap): 1:250-1:2000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD6 (rM CD6; TMPY-02254; Q91WN5; Met1-Gly396).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景T-cell differentiation antigen CD6, also known as TP12 and CD6, is a single-pass type I membrane protein which contains threeSRCR domains. CD6 / TP12 is a cell surface glycoprotein expressed primarily on T cells, it may function as a costimulatory molecule and may play a role in autoreactive immune responses. CD6 / TP12 is expressed by thymocytes, mature T-cells, a subset of B-cells known as B-1 cells, and by some cells in the brain. CD6 ligand termed CD166 (previously known as activated leukocyte cell adhesion molecule, ALCAM ) has been identified and shown to be expressed on activated T cells, B cells, thymic epithelium, keratinocytes, and in rheumatoid arthritis synovial tissue. CD6 / TP12 binds to activated leukocyte cell adhesion molecule ( CD166 ), and is considered as a costimulatory molecule involved in lymphocyte activation and thymocyte development. CD6 / TP12 partially associates with the TCR / CD3 complex and colocalizes with it at the center of the mature immunological synapse (IS) on T lymphocytes. During thymic development CD6-dependent signals may contribute both to thymocyte survival, and to the overall functional avidity of selection in both man and mouse.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Mouse CD6 protein (TMPY-02254)
抗原种属
Mouse
研究领域
ITIM/ITAM Immunoreceptors and Related Molecules
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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