购物车
全部删除
您的购物车当前为空
Anti-GPR4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 GPR4。Anti-GPR4 Polyclonal Antibody 可用于 WB,FCM。
Anti-GPR4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 GPR4。Anti-GPR4 Polyclonal Antibody 可用于 WB,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
| 产品描述 | Anti-GPR4 Polyclonal Antibody is a Rabbit antibody targeting GPR4. Anti-GPR4 Polyclonal Antibody can be used in WB,FCM. |
| Ig Type | IgG |
| 反应种属 | Human,Mouse |
| 应用 | WBFCM |
| 推荐剂量 | WB: 1:500-2000; FCM: 1μg/Test |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell membrane ; Multi-pass membrane protein Sequence Analysis |
| 组织特异性 | Expressed in omental fat pad and 141 other cell types or tissues |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Enables G protein-coupled receptor activity. Involved in several processes, including G protein-coupled receptor signaling pathway; positive regulation of Rho protein signal transduction; and response to acidic pH. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] |
| 免疫原 | KLH conjugated synthetic peptide: human G protein coupled receptor 4 |
| 抗原种属 | Human |
| 基因名称 | GPR4 |
| 基因ID | |
| 蛋白名称 | G-protein coupled receptor 4 |
| Uniprot ID | |
| 功能 | Proton-sensing G-protein coupled receptor couples to multiple intracellular signaling pathways, including GNAS/cAMP, GNAQ/phospholipase C (PLC), and GNA12/GNA13/Rho pathways (PubMed:12955148, PubMed:17462861, PubMed:20211729, PubMed:22110680).Acidosis-induced GPR4 activation increases paracellular gap formation and permeability of vascular endothelial cells through the GNA12/GNA13/Rho GTPase signaling pathway (PubMed:32058960).In the brain may mediate central respiratory sensitivity to CO2H+ (By similarity). |
| 分子量 | Theoretical: 41 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |