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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Alpha-Synuclein Polyclonal Antibody

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货号 TMAB-00107

别名 α-synuclein, Snca, Non-A4 component of amyloid precursor, Non-A β component of AD amyloid, Non-A beta component of AD amyloid, NACP, Alpha-synuclein

Anti-Alpha-Synuclein Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Alpha-Synuclein。Anti-Alpha-Synuclein Polyclonal Antibody 可用于 WB。

Anti-Alpha-Synuclein Polyclonal Antibody

Anti-Alpha-Synuclein Polyclonal Antibody

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货号 TMAB-00107 别名 α-synuclein, Snca, Non-A4 component of amyloid precursor, Non-A β component of AD amyloid, Non-A beta component of AD amyloid, NACP, Alpha-synuclein

Anti-Alpha-Synuclein Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Alpha-Synuclein。Anti-Alpha-Synuclein Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
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产品介绍

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产品描述
Anti-Alpha-Synuclein Polyclonal Antibody is a Rabbit antibody targeting Alpha-Synuclein. Anti-Alpha-Synuclein Polyclonal Antibody can be used in WB.
别名α-synuclein, Snca, Non-A4 component of amyloid precursor, Non-A β component of AD amyloid, Non-A beta component of AD amyloid, NACP, Alpha-synuclein
Ig Type
IgG
反应种属
Human,Mouse,Rat
验证活性
25 μg total protein per Lane of various lysates probed with Alpha-Synucleusn polyclonal antibody, unconjugated (TMAB-00107) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min.
verifiedActivity
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Membrane. Nucleus. Cell junction, synapse. Note=Membrane-bound in dopaminergic neurons.
组织特异性Expressed principally in brain but is also expressed in low concentrations in all tissues examined except in liver. Concentrated in presynaptic nerve terminals.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016].
抗原信息
免疫原
Recombinant Protein: full length Alpha-Synuclein
基因名称
SNCA
蛋白名称
alpha-synuclein
研究领域
Tangles & Tau,Synuclein
功能
May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.
化学信息
分子量Theoretical: 14 kDa.
颜色Transparent
物理性状Liquid
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

计算器

  • 稀释 计算器

关键词

Non-A b component of AD amyloida-synuclein
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