Me-PMeOx(50)-N3 (MW 4.3kDa) is a click chemistry reagent. Click chemistry offers significant potential for linking nucleic acids, lipids, proteins, and other molecules due to its beneficial properties such as high yield, high specificity, and simplicity, making it valuable in numerous research fields. This compound contains an Azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition reactions (SPAAC) with molecules containing DBCO or BCN groups.