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顶部生物活性储存和溶解信息计算器

Anti-Phospho-RPS6KA5 (Thr581) Polyclonal Antibody

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Anti-Phospho-RPS6KA5 (Thr581) Polyclonal Antibody
产品编号 TMAC-02656
别名 S6K-alpha-5, S6K alpha 5, RSK-like protein kinase, RSKL, RSK Like Protein Kinase, RPS6KA5 (p-Thr581), RPS6KA5 (p-T581), RLPK, Ribosomal protein S6 kinase alpha-5, Ribosomal Protein S6 Kinase Alpha 5, Ribosomal protein S6 kinase 90kD polypeptide 5, p-RPS6KA5 (Thr581), p-RPS6KA5 (T581), Phospho-RPS6KA5 (T581), Nuclear Mitogen And Stress Activated Protein Kinase 1, MSPK1, Mitogen and stress activated protein kinase 1, MGC1911, KS6A5_HUMAN, EC 2.7.11.1, 90 kDa ribosomal protein S6 kinase 5

Anti-Phospho-RPS6KA5 (Thr581) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-RPS6KA5 (Thr581)。Anti-Phospho-RPS6KA5 (Thr581) Polyclonal Antibody 可用于 WB,IHC-P,ICC/IF,ELISA。

Anti-Phospho-RPS6KA5 (Thr581) Polyclonal Antibody

Anti-Phospho-RPS6KA5 (Thr581) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-RPS6KA5 (Thr581) Polyclonal Antibody
产品编号 TMAC-02656 别名 S6K-alpha-5, S6K alpha 5, RSK-like protein kinase, RSKL, RSK Like Protein Kinase, RPS6KA5 (p-Thr581), RPS6KA5 (p-T581), RLPK, Ribosomal protein S6 kinase alpha-5, Ribosomal Protein S6 Kinase Alpha 5, Ribosomal protein S6 kinase 90kD polypeptide 5, p-RPS6KA5 (Thr581), p-RPS6KA5 (T581), Phospho-RPS6KA5 (T581), Nuclear Mitogen And Stress Activated Protein Kinase 1, MSPK1, Mitogen and stress activated protein kinase 1, MGC1911, KS6A5_HUMAN, EC 2.7.11.1, 90 kDa ribosomal protein S6 kinase 5

Anti-Phospho-RPS6KA5 (Thr581) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-RPS6KA5 (Thr581)。Anti-Phospho-RPS6KA5 (Thr581) Polyclonal Antibody 可用于 WB,IHC-P,ICC/IF,ELISA。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,245
5日内发货
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产品描述
Anti-Phospho-RPS6KA5 (Thr581) Polyclonal Antibody is a Rabbit antibody targeting Phospho-RPS6KA5 (Thr581). Anti-Phospho-RPS6KA5 (Thr581) Polyclonal Antibody can be used in WB,IHC-P,ICC/IF,ELISA.
别名S6K-alpha-5, S6K alpha 5, RSK-like protein kinase, RSKL, RSK Like Protein Kinase, RPS6KA5 (p-Thr581), RPS6KA5 (p-T581), RLPK, Ribosomal protein S6 kinase alpha-5, Ribosomal Protein S6 Kinase Alpha 5, Ribosomal protein S6 kinase 90kD polypeptide 5, p-RPS6KA5 (Thr581), p-RPS6KA5 (T581), Phospho-RPS6KA5 (T581), Nuclear Mitogen And Stress Activated Protein Kinase 1, MSPK1, Mitogen and stress activated protein kinase 1, MGC1911, KS6A5_HUMAN, EC 2.7.11.1, 90 kDa ribosomal protein S6 kinase 5
Ig Type
IgG
交叉反应
Human,Mouse
应用
WB
IHC-P
ICC/IF
ELISA
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-300; ICC/IF: 1:200-1000; ELISA: 1:40000
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
性状Liquid
缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
研究背景catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Appears to be activated by multiple phosphorylations on threonine and serine residues. ERK1/2 and MAPK14/p38-alpha may play a role in this process.,function:Serine/threonine kinase required for the mitogen or stress-induced phosphorylation of the transcription factors CREB (cAMP response element-binding protein) and ATF1 (activating transcription factor-1). Essential role in the control of RELA transcriptional activity in response to TNF. Directly represses transcription via phosphorylation of 'Ser-1' of histone H2A. Phosphorylates 'Ser-10' of histone H3 in response to mitogenics, stress stimuli and epidemal growth-factor (EGF), which results in the transcriptional activation of several immediate early genes, including proto-oncogenes c-fos/FOS and c-jun/JUN. May also phosphorylate 'Ser-28' of histone H3. Mediates the mitogen- and stress-induced phosphorylation of high mobility group protein 14 (HMG-14).,miscellaneous:Enzyme activity requires the presence of both kinase domains.,PTM:Ser-376 and Thr-581 phosphorylation is required for kinase activity. Ser-376 and Ser-212 are autophosphorylated by the C-terminal kinase domain, and their phosphorylation is essential for the catalytic activity of the N-terminal kinase domain.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 2 protein kinase domains.,subcellular location:Predominantly nuclear. Partially cytoplasmic.,subunit:Forms a complex with either ERK1 or ERK2 in quiescent cells which transiently dissociates following mitogenic stimulation. Also associates with MAPK14/p38-alpha. Activated RPS6KA5 associates with and phosphorylates the NF-kappa-B p65 subunit RELA.,tissue specificity:Widely expressed with high levels in heart, brain and placenta. Less abundant in lung, kidney and liver.,
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
A synthesized phosphopeptide: human MSK1 around the phosphorylation site of Thr581. AA range:551-600
抗原种属
human
Uniprot ID
O75582
化学信息
分子量Actual: 90 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

RPS6KA5 (pThr581)RPS6KA5 (pT581)RPS6KA5 (phospho-Thr581)RPS6KA5 (phospho-T581)pRPS6KA5 (Thr581)pRPS6KA5 (T581)

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