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Anti-Aquaporin-4/AQP4 Antibody (8R110)

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产品编号 TMAH-00077

Anti-Aquaporin-4/AQP4 Antibody (8R110) 是一种抗体,靶向 Aquaporin-4/AQP4。Anti-Aquaporin-4/AQP4 Antibody (8R110) 可用于 ELISA, IHC。

Anti-Aquaporin-4/AQP4 Antibody (8R110)

Anti-Aquaporin-4/AQP4 Antibody (8R110)

Rating icon 还可以
产品编号 TMAH-00077

Anti-Aquaporin-4/AQP4 Antibody (8R110) 是一种抗体,靶向 Aquaporin-4/AQP4。Anti-Aquaporin-4/AQP4 Antibody (8R110) 可用于 ELISA, IHC。

规格价格库存数量
50 μL
¥ 1,305
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100 μL
¥ 2,190
5日内发货
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产品介绍

生物活性
产品描述
Anti-Aquaporin-4/AQP4 Antibody (8R110) is an antibody targeting Aquaporin-4/AQP4. Anti-Aquaporin-4/AQP4 Antibody (8R110) can be used in ELISA, IHC.
Ig Type
Rabbit IgG
克隆号
8R110
交叉反应
Human
验证活性
IHC image of TMAH-00077 diluted at 1:50 and staining in paraffin-embedded human lung cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.33% DAB.
应用
ELISA, IHC
推荐剂量
IHC:1:50-1:200.
抗体种类
Monoclonal
亚细胞定位Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Endosome membrane. Cell membrane, sarcolemma; Multi-pass membrane protein. Cell projection.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Forms a water-specific channel. Plays an important role in brain water homeostasis and in glymphatic solute transport. Required for a normal rate of water exchange across the blood brain interface. Required for normal levels of cerebrospinal fluid influx into the brain cortex and parenchyma along paravascular spaces that surround penetrating arteries, and for normal drainage of interstitial fluid along paravenous drainage pathways. Thereby, it is required for normal clearance of solutes from the brain interstitial fluid, including soluble beta-amyloid peptides derived from APP. Plays a redundant role in urinary water homeostasis and urinary concentrating ability.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: Human AQP4
抗原种属
Human
基因ID
361
Uniprot ID
研究领域
Cancer, Metabolism, Signal transduction
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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