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Anti-KRT16 Antibody (3O311)

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Anti-KRT16 Antibody (3O311)
产品编号 TMAC-01078
别名 type I cytoskeletal 16, KRT16A, KRT16, Keratin-16 (K16), Keratin, type I cytoskeletal 16, Cytokeratin-16 (CK-16)

Anti-KRT16 Antibody (3O311) 是一种 Rabbit 抗体,靶向 KRT16。Anti-KRT16 Antibody (3O311) 可用于 WB,ICC/IF,IHC,FCM。

Anti-KRT16 Antibody (3O311)

Anti-KRT16 Antibody (3O311)

Rating icon 还可以
Anti-KRT16 Antibody (3O311)
产品编号 TMAC-01078 别名 type I cytoskeletal 16, KRT16A, KRT16, Keratin-16 (K16), Keratin, type I cytoskeletal 16, Cytokeratin-16 (CK-16)

Anti-KRT16 Antibody (3O311) 是一种 Rabbit 抗体,靶向 KRT16。Anti-KRT16 Antibody (3O311) 可用于 WB,ICC/IF,IHC,FCM。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-KRT16 Antibody (3O311) is a Rabbit antibody targeting KRT16. Anti-KRT16 Antibody (3O311) can be used in WB,ICC/IF,IHC,FCM.
别名type I cytoskeletal 16, KRT16A, KRT16, Keratin-16 (K16), Keratin, type I cytoskeletal 16, Cytokeratin-16 (CK-16)
Ig Type
IgG
交叉反应
Human
验证活性
1. Western blot analysis of Cytokeratin 16 on human skin lysates using anti-Cytokeratin 16 antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Cytokeratin 16 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-Cytokeratin 16 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-Cytokeratin 16 antibody. Counter stained with hematoxylin.
5. ICC staining Cytokeratin 16 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
6. ICC staining Cytokeratin 16 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
7. ICC staining Cytokeratin 16 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
8. Flow cytometric analysis of HepG2 cells with Cytokeratin 16 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
应用
推荐剂量
WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Cytokeratins comprise a diverse group of intermediate filament proteins that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. The cytokeratin proteins play a critical role in differentiation, as well as tissue specialization and function, to maintain the overall structural integrity of epithelial cells. Cytokeratins are also useful markers in identifying the origin of metastatic tumors. Cytokeratin 16 is expressed in benign stratified squamous epithelium and squamous cell carcinoma of the head and neck, as well as luminal cells of mammary gland and sweat ducts. It is absent in noninvasive breast carcinomas and normal breast tissue. Mutations in the Cytokeratin 16 gene cause various diseases, including pachyonychia congenita type 1 (PC1), nonepidermolytic palmoplantar keratoderma (NEPPK) and unilateral palmoplantar verrucous nevus (UPVN).
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 51 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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