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Anti-Oncostatin M/OSM Antibody (9V884)
还可以产品编号 TMAY-00849
Anti-Oncostatin M/OSM Antibody (9V884) 是一种 Rabbit 抗体，靶向 Oncostatin M/OSM。Anti-Oncostatin M/OSM Antibody (9V884) 可用于 ELISA,ICC/IF。
Anti-Oncostatin M/OSM Antibody (9V884)
Anti-Oncostatin M/OSM Antibody (9V884)
还可以产品编号 TMAY-00849
Anti-Oncostatin M/OSM Antibody (9V884) 是一种 Rabbit 抗体，靶向 Oncostatin M/OSM。Anti-Oncostatin M/OSM Antibody (9V884) 可用于 ELISA,ICC/IF。
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-Oncostatin M/OSM Antibody (9V884) is a Rabbit antibody targeting Oncostatin M/OSM. Anti-Oncostatin M/OSM Antibody (9V884) can be used in ELISA,ICC/IF. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 9V884 |
| 交叉反应 | Human |
| 验证活性 | Immunofluorescence staining of OSM in jurkat cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS,blocked with 10% serum, and incubated with rabbit anti-human OSM monoclonal antibody (dilution ratio 1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to Cytoplasm . |
| 应用 | ELISA,ICC/IF |
| 推荐剂量 | ELISA: 1:5000-1:10000; ICC-IF: 1:20-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human Oncostatin M / OSM (rh Oncostatin M / OSM; TMPY-02364; P13725; Met1-Arg221). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that has functions mainly in cell growth. Oncostatin M (OSM) is considered as a pleiotropic cytokine that signals through cell surface receptors typeⅠand typeⅡ both of which share the similarity of containing protein gp130 and takes part in many bio metabolism processes including liver development, hematopoiesis, inflammation, bone formation, and destruction and possibly CNS development. Oncostatin M (OSM) was previously identified by its ability to inhibit the growth of cells from melanoma and other solid tumors. It also has been reported that OSM, like LIF, IL-6, and G-CSF, can inhibit the proliferation of murine M1 myeloid leukemic cells and can induce their differentiation into macrophage-like cells. The human form of OSM is insensitive between pH2 and 11 and resistant to heating for one hour at 56 degrees but is not stable at 90 degrees. The human OSM is produced as a precursor containing 252 amino acids, whose first 25 amino acids function as a secretory signal peptide and which on removal yields the soluble 227 amino acid pro-OSM. Removal of the C-terminal most 31 amino acids produces the fully active 196 residue form. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human Oncostatin M / OSM protein (TMPY-02364) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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