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顶部生物活性储存和溶解信息计算器

Anti-IFNL2 Monoclonal Antibody

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产品编号 TMAZ-0009

别名 Interleukin-28A, Interferon lambda-2, Cytokine Zcyto20

Anti-IFNL2 Monoclonal Antibody is a humanized rabbit antibody targeting IFNL2. Anti-IFNL2 Monoclonal Antibody can be used in ELISA, FCM. 可用于 ELISA,FCM。

Anti-IFNL2 Monoclonal Antibody

Anti-IFNL2 Monoclonal Antibody

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产品编号 TMAZ-0009 别名 Interleukin-28A, Interferon lambda-2, Cytokine Zcyto20

Anti-IFNL2 Monoclonal Antibody is a humanized rabbit antibody targeting IFNL2. Anti-IFNL2 Monoclonal Antibody can be used in ELISA, FCM. 可用于 ELISA,FCM。

规格价格库存数量
25 μg
¥ 1,250
7日内发货
50 μg
¥ 1,500
7日内发货
100 μg
¥ 2,099
7日内发货
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TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
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浓度:0.24 mg/mL
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产品介绍

生物活性
产品描述
Anti-IFNL2 Monoclonal Antibody is a humanized rabbit antibody targeting IFNL2. Anti-IFNL2 Monoclonal Antibody can be used in ELISA,FCM.
别名Interleukin-28A, Interferon lambda-2, Cytokine Zcyto20
Ig Type
Rabbit monoclonal IgG
交叉反应
Human
验证活性
Flow cytometry analysis of IFNL2 overexpressed 410F cells with TMAZ-0009, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line).
应用ELISAFCM
推荐剂量
0.1-0.2 μg/10E6 cells for FCM; 1 ng/μl for ELISA
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Secreted
构建方式This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of IFNL2 protein.
纯化方式Protein A Affinity Purified
性状Liquid
缓冲液0.22 μm filtered solution in PBS.
纯度> 95% as determined by SDS-PAGE.
研究背景Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Biotin
可提供抗体种类
2
抗原信息
免疫原
IFNL2
抗原种属
Human
基因ID
282616
Uniprot ID
Q8IZJ0
研究领域
Immunology Research
化学信息
分子量150 kDa
颜色Transparent
物理性状Liquid
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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