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Gigantol

Name: Gigantol
Brand: TargetMol
SKU: TN7033
Price: 833 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 99.96%

货号 TN7033Cas号 83088-28-2

别名 石斛酚, 3,4'-dihydroxy-5,5'-dimethoxybibenzyl

Gigantol(Dendrophenol) (3,4'-dihydroxy-5,5'-dimethoxybibenzyl) 是从铁皮石斛的茎中分离得到的。

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Gigantol

一键复制产品信息

很棒

纯度: 99.96%

货号 TN7033 别名 石斛酚, 3,4'-dihydroxy-5,5'-dimethoxybibenzylCas号 83088-28-2

Gigantol(Dendrophenol) (3,4'-dihydroxy-5,5'-dimethoxybibenzyl) 是从铁皮石斛的茎中分离得到的。

规格	价格	库存
1 mg	¥ 833	现货
5 mg	¥ 1,820	现货
10 mg	¥ 2,730	现货
25 mg	¥ 4,480	现货
50 mg	¥ 6,280	现货
100 mg	¥ 8,490	现货
200 mg	¥ 11,300	现货
1 mL x 10 mM (in DMSO)	¥ 1,930	现货

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TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

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纯度: 99.96%

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资源下载:

COA LCMS HNMR 产品操作手册

产品介绍

Gigantol AI Summary

Gigantol demonstrates a diverse range of biological activities including antioxidant, anti-inflammatory, spasmolytic, cytotoxic, antifungal, antiproliferative, and enzyme inhibitory effects. It exhibits antioxidant activity with an IC50 of 56400.0 nM in a DPPH radical scavenging assay. The compound shows anti-inflammatory effects by inhibiting nitric oxide (NO) production in LPS and TNF-alpha activated murine RAW 264.7 cells (IC50 of 32900.0 nM) and inhibiting superoxide anion generation (IC50 of 2100.0 nM) and elastase release (IC50 of 3200.0 nM) in human neutrophils. Moreover, it demonstrates spasmolytic activity with an IC50 of 260.0 nM in the guinea pig ileum and also inhibits bovine brain CaM-dependent PDE with an IC50 of 7000.0 nM. In cytotoxicity assays, it is active against several human cancer cell lines, including HepG2 (IC50 of 1883.0 nM) and HCCLM3 (IC50 of 57900.0 nM), as well as human NCI-H460 cells. The compound also affects cell migration and shows significant inhibition in wound healing and Boyden chamber assays. Additionally, Gigantol displays antifungal activity against multiple fungi strains with MIC values ranging from 91200.0 nM to 365000.0 nM. It also has enzyme inhibitory effects, shown by its inhibition of pyruvate carboxylase in HCCLM3 cell lysate (IC50 of 125.0 nM), alpha-glucosidase, PTP1B, and aldose reductase with various IC50 values. Finally, it demonstrates considerable inhibitory effects on calmodulin-dependent PDE1 activity (IC50 of 114180.0 nM) and has antiproliferative activity against multiple cancer cells including HeLa, MCF7, and A549 with IC50 values greater than 10000.0 nM..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Gigantol(Dendrophenol) (3,4'-dihydroxy-5,5'-dimethoxybibenzyl) is isolated from the stems of Dendrobium candidum.
别名	石斛酚, 3,4'-dihydroxy-5,5'-dimethoxybibenzyl

化学信息

分子量	274.31
分子式	C₁₆H₁₈O₄
CAS No.	83088-28-2
Smiles	C(CC1=CC(OC)=C(O)C=C1)C2=CC(OC)=CC(O)=C2
密度	1.204 g/cm3 (Predicted)

储存&溶解度

存储

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 72.5 mg/mL (264.3 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.6455 mL	18.2276 mL	36.4551 mL	182.2755 mL
5 mM	0.7291 mL	3.6455 mL	7.2910 mL	36.4551 mL
10 mM	0.3646 mL	1.8228 mL	3.6455 mL	18.2276 mL
20 mM	0.1823 mL	0.9114 mL	1.8228 mL	9.1138 mL
50 mM	0.0729 mL	0.3646 mL	0.7291 mL	3.6455 mL
100 mM	0.0365 mL	0.1823 mL	0.3646 mL	1.8228 mL

计算器

摩尔浓度计算器
稀释计算器
配液计算器
分子量计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH₂O，那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 100 μL DMSO （母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。