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IGF2/IGF-II Protein, Human, Recombinant (hFc)

Synonyms: 胰岛素样生长因子, Somatomedin-A, Somatomedin A, PP1446, IGF-II, IGF2
货号 TMPK-00061 一键复制产品信息
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The insulin family consists of insulin, insulin-like growth factor 1 (IGF-1), insulin-like growth factor 2 (IGF-2), their receptors (IR, IGF-1R and IGF-2R), and their binding proteins. All three ligands are involved in cell proliferation, apoptosis, protein synthesis and metabolism due to their homologous sequences and structural similarities. Insulin-like growth factor 2, a member of the insulin family, plays an important role in embryonic development, metabolic disorders, and tumorigenesis by combining with three receptors with different degrees of affinity.

IGF2/IGF-II Protein, Human, Recombinant (hFc)

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货号 TMPK-00061

别名 胰岛素样生长因子, Somatomedin-A, Somatomedin A, PP1446, IGF-II, IGF2

The insulin family consists of insulin, insulin-like growth factor 1 (IGF-1), insulin-like growth factor 2 (IGF-2), their receptors (IR, IGF-1R and IGF-2R), and their binding proteins. All three ligands are involved in cell proliferation, apoptosis, protein synthesis and metabolism due to their homologous sequences and structural similarities. Insulin-like growth factor 2, a member of the insulin family, plays an important role in embryonic development, metabolic disorders, and tumorigenesis by combining with three receptors with different degrees of affinity.

IGF2/IGF-II Protein, Human, Recombinant (hFc)
其他形式的 “IGF2/IGF-II Protein, Human, Recombinant (hFc)”:
规格价格库存数量
5 μg
¥ 426
3日内发货
10 μg
¥ 681
3日内发货
20 μg
¥ 1,090
3日内发货
50 μg
¥ 1,960
3日内发货
100 μg
¥ 3,130
现货
200 μg
¥ 5,000
5日内发货
500 μg
¥ 9,000
5日内发货
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选择批次:
纯度: > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
颜色: 白色
性状: Lyophilized powder
资源下载: COA重组蛋白用户指南

产品介绍


生物活性
产品描述
The insulin family consists of insulin, insulin-like growth factor 1 (IGF-1), insulin-like growth factor 2 (IGF-2), their receptors (IR, IGF-1R and IGF-2R), and their binding proteins. All three ligands are involved in cell proliferation, apoptosis, protein synthesis and metabolism due to their homologous sequences and structural similarities. Insulin-like growth factor 2, a member of the insulin family, plays an important role in embryonic development, metabolic disorders, and tumorigenesis by combining with three receptors with different degrees of affinity.
生物活性
Immobilized Human IGFBP-3, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Human IGF II, hFc Tag with the EC50 of 0.19μg/ml determined by ELISA.
研究背景
The insulin family consists of insulin, insulin-like growth factor 1 (IGF-1), insulin-like growth factor 2 (IGF-2), their receptors (IR, IGF-1R and IGF-2R), and their binding proteins. All three ligands are involved in cell proliferation, apoptosis, protein synthesis and metabolism due to their homologous sequences and structural similarities. Insulin-like growth factor 2, a member of the insulin family, plays an important role in embryonic development, metabolic disorders, and tumorigenesis by combining with three receptors with different degrees of affinity.
种属
Human
表达系统
HEK293 Cells
标签
N-hFc
蛋白编号P01344-1
蛋白构建
Ala25-Glu91
蛋白纯度
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状
Lyophilized powder
缓冲液
Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法
Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名
胰岛素样生长因子, Somatomedin-A, Somatomedin A, PP1446, IGF-II, IGF2
内毒素< 1.0 EU/μg of the protein as determined by the LAL method.
化学信息
分子量33.00 kDa (predicted). Due to glycosylation, the protein migrates to 35-45 kDa based on Tris-Bis PAGE result.
储存&溶解度
运输方式In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

计算器

  • 复溶 计算器
  • 重组蛋白稀释 计算器
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剂量转换

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技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.
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