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DSG-2/Desmoglein-2 Protein, Human, Recombinant (His)
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货号 TMPK-00967
别名 MGC117037, MGC117036, HDGC, DSG2, Desmoglein-2, CMD1BB, CDHF5, ARVC10
Desmoglein-2 (DSG-2) as the primary high-affinity receptor used by adenoviruses Ad3, Ad7, Ad11 and Ad14. These serotypes represent key human pathogens causing respiratory and urinary tract infections. In epithelial cells, adenovirus binding of DSG-2 triggers events reminiscent of epithelial-to-mesenchymal transition, leading to transient opening of intercellular junctions. DSG-2/Desmoglein-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 63.6 kDa and the accession number is Q14126.
其他形式的 “DSG-2/Desmoglein-2 Protein, Human, Recombinant (His)”:
DSG-2/Desmoglein-2 Protein, Human, Recombinant (His)
一键复制产品信息 很棒SPR兼容缓冲液
货号 TMPK-00967 别名 MGC117037, MGC117036, HDGC, DSG2, Desmoglein-2, CMD1BB, CDHF5, ARVC10
Desmoglein-2 (DSG-2) as the primary high-affinity receptor used by adenoviruses Ad3, Ad7, Ad11 and Ad14. These serotypes represent key human pathogens causing respiratory and urinary tract infections. In epithelial cells, adenovirus binding of DSG-2 triggers events reminiscent of epithelial-to-mesenchymal transition, leading to transient opening of intercellular junctions. DSG-2/Desmoglein-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 63.6 kDa and the accession number is Q14126.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 313 | 现货 | |
| 10 μg | ¥ 498 | 现货 | |
| 20 μg | ¥ 793 | 3日内发货 | |
| 50 μg | ¥ 1,580 | 3日内发货 | |
| 100 μg | ¥ 2,660 | 现货 | |
| 200 μg | ¥ 4,790 | 5日内发货 | |
| 500 μg | ¥ 10,600 | 5日内发货 |
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产品介绍
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化学信息
储存&溶解度
| 产品描述 | Desmoglein-2 (DSG-2) as the primary high-affinity receptor used by adenoviruses Ad3, Ad7, Ad11 and Ad14. These serotypes represent key human pathogens causing respiratory and urinary tract infections. In epithelial cells, adenovirus binding of DSG-2 triggers events reminiscent of epithelial-to-mesenchymal transition, leading to transient opening of intercellular junctions. DSG-2/Desmoglein-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 63.6 kDa and the accession number is Q14126. |
| 生物活性 | Immobilized Human DSG-2, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-DSG-2 Antibody, hFc Tag with the EC50 of 10.7ng/ml determined by ELISA. |
| 研究背景 | Desmoglein-2 (DSG-2) as the primary high-affinity receptor used by adenoviruses Ad3, Ad7, Ad11 and Ad14. These serotypes represent key human pathogens causing respiratory and urinary tract infections. In epithelial cells, adenovirus binding of DSG-2 triggers events reminiscent of epithelial-to-mesenchymal transition, leading to transient opening of intercellular junctions. |
| 种属 | Human |
| 表达系统 | HEK293 Cells |
| 标签 | C-His |
| 蛋白编号 | Q14126 |
| 蛋白构建 | Ala50-Gly609 |
| 蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| 蛋白性状 | Lyophilized powder |
| 缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| 复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 别名 | MGC117037, MGC117036, HDGC, DSG2, Desmoglein-2, CMD1BB, CDHF5, ARVC10 |
| 内毒素 | < 1 EU/μg by the LAL method. |
| 分子量 | 63.6 kDa (predicted). Due to glycosylation, the protein migrates to 75-80 kDa based on Tris-Bis PAGE result. |
| 颜色 | White |
| 物理性状 | Lyophilized powder |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. |
| 存储 | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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