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Anti-CD5 Antibody-APC (1Q411) 是一种 APC-conjugated Mouse 抗体,靶向 CD5。Anti-CD5 Antibody-APC (1Q411) 可用于 FCM。
Anti-CD5 Antibody-APC (1Q411) 是一种 APC-conjugated Mouse 抗体,靶向 CD5。Anti-CD5 Antibody-APC (1Q411) 可用于 FCM。
产品描述 | Anti-CD5 Antibody-APC (1Q411) is a APC-conjugated Mouse antibody targeting CD5. Anti-CD5 Antibody-APC (1Q411) can be used in FCM. |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 1Q411 |
交叉反应 | Rat |
验证活性 | Flow cytometric analysis of Rat CD5 expression on SD rat splenocytes. Cells were stained with APC-conjugated anti-Rat CD5. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
应用 | FCM |
推荐剂量 | 5 μl/Test, 0.1 mg/ml |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rat CD5 / Cluster of Differentiation 5 (rR CD5 / Cluster of Differentiation 5; TMPY-03169; P51882; Met1-Pro368) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
研究背景 | The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD5 is a member of the CD system. CD5 was found to be widely distributed in T-cells and B1 cells which is a subset of IgM-secreting B cells. CD5 also was found expressed in small lymphocytic lymphoma, hairy cell leukaemia and mantle cell lymphoma cells. CD5 serves to weaken the activating stimulus from the BCR so that the B1 cells can only reflect to the very strong stimuli but not the normal tissue proteins. |
偶联 | APC |
其他可选修饰符 | Unconjugated/FITC/PE |
可提供抗体种类 | 4 |
免疫原 | Recombinant Rat CD5 / Cluster of Differentiation 5 Protein (TMPY-03169) |
抗原种属 | Rat |
研究领域 | ITIM/ITAM Immunoreceptors and Related Molecules |
储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
运输方式 | Shipping with blue ice. |
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