The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
10 μg | ¥ 810 | 现货 | ||
20 μg | ¥ 1,320 | 5日内发货 | ||
50 μg | ¥ 2,470 | 5日内发货 | ||
100 μg | ¥ 4,010 | 5日内发货 |
产品描述 | The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration. |
种属 | Human |
表达系统 | E.coli |
标签 | Tag Free |
蛋白编号 | P01138 |
别名 | β-NGF, NGF, NGFB, Beta-NGF, Beta-Nerve Growth Factor, pro-Beta NGF, β-Nerve Growth Factor, 神经生长因子, pro-β NGF |
氨基酸序列 | Glu19-Ala241 |
蛋白构建 | Recombinant Human pro-Nerve Growth Factor is produced by our E.coli expression system and the target gene encoding Glu19-Ala241 is expressed. |
蛋白纯度 |
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
|
内毒素 | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
缓冲液 | Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl,500mM NaCl,5%Trehalose,5%Mannitol,0.01%tween80,1mM EDTA,pH8.0. |
复溶方法 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
存储 |
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
运输方式 |
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
研究背景 | The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration. |
bottom
您可能有的问题的答案可以在重组蛋白操作手册中找到
pro-Beta NGF Protein, Human, Recombinant b-Nerve Growth Factor β-NGF NGF NGFB Beta-NGF Beta-Nerve Growth Factor pro-Beta NGF β-Nerve Growth Factor 神经生长因子 pro-β NGF b-NGF pro-b NGF recombinant recombinant-proteins proteins protein