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Anti-SPARCL1 Antibody-FITC (5B937)
还可以产品编号 TMAY-00164F
Anti-SPARCL1 Antibody-FITC (5B937) 是一种 FITC-conjugated Mouse 抗体，靶向 SPARCL1。Anti-SPARCL1 Antibody-FITC (5B937) 可用于 FCM。
Anti-SPARCL1 Antibody-FITC (5B937)
Anti-SPARCL1 Antibody-FITC (5B937)
还可以产品编号 TMAY-00164F
Anti-SPARCL1 Antibody-FITC (5B937) 是一种 FITC-conjugated Mouse 抗体，靶向 SPARCL1。Anti-SPARCL1 Antibody-FITC (5B937) 可用于 FCM。
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抗原信息
| 产品描述 | Anti-SPARCL1 Antibody-FITC (5B937) is a FITC-conjugated Mouse antibody targeting SPARCL1. Anti-SPARCL1 Antibody-FITC (5B937) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 5B937 |
| 交叉反应 | Human |
| 验证活性 | Profile of anti-SPARCL1 reactivity on HL60 cells analyzed by flow cytometry. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), and stained with FITC conjugated Mouse anti-SPARCL1, The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | FCM |
| 推荐剂量 | 10 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SPARCL1 (rh SPARCL1; NP_004675.3Met 1-Phe 664) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | SPARC-like protein 1 (SPARCL1; also known as SC1, high endothelial venule protein, or hevin) is an extracellular matrix-associated, secreted glycoprotein belonging to the secreted protein acidic and rich in cysteine (SPARC) family of matricellular proteins. It contains three conserved structural domains that are implicated in the regulation of cell adhesion, migration, and proliferation. SPARCL1 is expressed during embryogenesis and tissue remodeling and is especially prominent in brain and vasculature. Its down-regulation in a number of cancers and the possibility of its functional compensation by SPARC has led to recent interest in hevin as a tumor suppressor and regulator of angiogenesis. SPARCL1 has antiadhesive properties, and loss of SPARCL1 expression is associated with increased proliferative activity and cell cycle progression. It is suggested that it may influence multiple cellular processes during distinct stages of brain development and function. Besides, SPARCL1 can influence the function of astroglial cells in the developing and mature central nervous system (CNS). |
| 偶联 | FITC |
| 其他可选修饰符 | Unconjugated/PE |
| 可提供抗体种类 | 3 |
| 免疫原 | Recombinant Human SPARCL1 protein |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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