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Anti-Leptin receptor Polyclonal Antibody 5

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货号 TMAB-08280

Anti-Leptin receptor Polyclonal Antibody 5 是一种 Rabbit 抗体，靶向 Leptin receptor。Anti-Leptin receptor Polyclonal Antibody 5 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Leptin receptor Polyclonal Antibody 5

Anti-Leptin receptor Polyclonal Antibody 5

一键复制产品信息
Rating icon 还可以
货号 TMAB-08280

Anti-Leptin receptor Polyclonal Antibody 5 是一种 Rabbit 抗体，靶向 Leptin receptor。Anti-Leptin receptor Polyclonal Antibody 5 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

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产品描述
Anti-Leptin receptor Polyclonal Antibody 5 is a Rabbit antibody targeting Leptin receptor. Anti-Leptin receptor Polyclonal Antibody 5 can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Dog,Pig,Horse)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Single-pass type I membrane protein. Isoform E: Secreted (Probable). Isoform A is expressed in fetal liver and in hematopoietic tissues and choroid plexus. In adults highest expression in heart, liver, small intestine, prostate and ovary. Low level in lung and kidney. Isoform B is highly expressed in hypothalamus.
组织特异性Isoform A is expressed in fetal liver and in hematopoietic tissues and choroid plexus. In adults highest expression in heart, liver, small intestine, prostate and ovary. Low level in lung and kidney. Isoform B is highly expressed in hypothalamus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
浓度1mg/ml
研究背景The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).[provided by RefSeq, Nov 2010]
抗原信息
免疫原
KLH conjugated synthetic peptide: human Leptin receptor
抗原种属
Human
基因名称
LEPR
基因ID
3953
蛋白名称
Leptin receptor
Uniprot ID
P48357
功能
Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway (By similarity).
化学信息
分子量Theoretical: 103/132 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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