Anti-IL-6 Antibody (1I87)

Name: Anti-IL-6 Antibody (1I87)
Brand: TargetMol
SKU: TMAY-00749
Rating: 4.5 (1 reviews)

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产品编号 TMAY-00749

Anti-IL-6 Antibody (1I87) 是一种 Mouse 抗体，靶向 IL-6。Anti-IL-6 Antibody (1I87) 可用于 IHC-P。

Anti-IL-6 Antibody (1I87)

还可以

产品编号 TMAY-00749

Anti-IL-6 Antibody (1I87) 是一种 Mouse 抗体，靶向 IL-6。Anti-IL-6 Antibody (1I87) 可用于 IHC-P。

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生物活性

产品描述	Anti-IL-6 Antibody (1I87) is a Mouse antibody targeting IL-6. Anti-IL-6 Antibody (1I87) can be used in IHC-P.
Ig Type	Monoclonal Mouse IgG1
克隆号	1I87
交叉反应	Human
验证活性	1. Immunochemical staining of human IL6 in human liver with mouse monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human IL6 in human cirrhosis with mouse monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
应用	IHC-P
推荐剂量	IHC-P: 1:100-1:500
抗体种类	Monoclonal
宿主来源	Mouse
构建方式	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL6 / IL-6 (rh IL6 / IL-6; TMPY-00863; NP_000591.1; Val30-Met212). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式	Protein A
性状	Liquid
缓冲液	0.2 μm filtered solution in PBS
研究背景	Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as a phosphorylated and variably glycosylated molecule. It exerts actions through its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affinity, and ubiquitously expressed glycoprotein 130 (gp130) that binds the IL-6. IL-6R complex with high affinity and thus transduces signals. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined as an essential role in directing the transition from innate to acquired immunity.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy

偶联与修饰

偶联	Unconjugated

抗原信息

免疫原	Recombinant Human IL6 / IL-6 protein (TMPY-00863)
抗原种属	Human
研究领域	Neuroinflammation, Cancer Drug Targets

存储&运输

储存方式	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式	Shipping with blue ice.