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别名 FLG, Filaggrin
Anti-Filaggrin Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Filaggrin。Anti-Filaggrin Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P。
Anti-Filaggrin Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Filaggrin。Anti-Filaggrin Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
| 产品描述 | Anti-Filaggrin Polyclonal Antibody is a Rabbit antibody targeting Filaggrin. Anti-Filaggrin Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P. |
| 别名 | FLG, Filaggrin |
| Ig Type | IgG |
| 反应种属 | Human,Rat (predicted:Mouse,Dog,Pig,Cow,Horse,Rabbit) |
| 验证活性 | 1. Tissue/cell: rat tongue tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Incubation: Anti-Filaggrin Polyclonal Antibody, Unconjugated (TMAB-00680) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining. 2. Tissue/cell: human skin tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Incubation: Anti-Filaggrin Polyclonal Antibody, Unconjugated (TMAB-00680) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining. ![]() ![]() |
| 应用 | IFIHC-FrIHC-P |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 组织特异性 | Keratohyalin granules. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1 mg/mL |
| 研究背景 | The protein encoded by this gene is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Mutations in this gene are associated with ichthyosis vulgaris.[provided by RefSeq, Dec 2009]. |
| 免疫原 | KLH conjugated synthetic peptide: human Filaggrin |
| 抗原种属 | Human |
| 基因名称 | FLG |
| 基因ID | |
| 蛋白名称 | Filaggrin |
| Uniprot ID | |
| 研究领域 | Epi / Endo-thelial,Cytokeratin,Cytokeratins |
| 功能 | Aggregates keratin intermediate filaments and promotes disulfide-bond formation among the intermediate filaments during terminal differentiation of mammalian epidermis. |
| 分子量 | Theoretical: 447 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | store at -20°C |