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顶部生物活性储存和溶解信息计算器

Anti-Phospho-p70 S6 Kinase (Ser 411) Antibody (7V681)

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Anti-Phospho-p70 S6 Kinase (Ser 411) Antibody (7V681)
产品编号 TMAC-03015
别名 p-p70 S6 Kinase (Ser 411), p-p70 S6 Kinase (S 411), p70 S6 Kinase (p-Ser 411), p70 S6 Kinase (p-S 411)

Anti-Phospho-p70 S6 Kinase (Ser 411) Antibody (7V681) 是一种 Mouse 抗体，靶向 Phospho-p70 S6 Kinase (Ser 411)。Anti-Phospho-p70 S6 Kinase (Ser 411) Antibody (7V681) 可用于 WB,IP,IF,IHC-P。

Anti-Phospho-p70 S6 Kinase (Ser 411) Antibody (7V681)

Anti-Phospho-p70 S6 Kinase (Ser 411) Antibody (7V681)

Rating icon 还可以
Anti-Phospho-p70 S6 Kinase (Ser 411) Antibody (7V681)
产品编号 TMAC-03015 别名 p-p70 S6 Kinase (Ser 411), p-p70 S6 Kinase (S 411), p70 S6 Kinase (p-Ser 411), p70 S6 Kinase (p-S 411)

Anti-Phospho-p70 S6 Kinase (Ser 411) Antibody (7V681) 是一种 Mouse 抗体，靶向 Phospho-p70 S6 Kinase (Ser 411)。Anti-Phospho-p70 S6 Kinase (Ser 411) Antibody (7V681) 可用于 WB,IP,IF,IHC-P。

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50 μL
¥ 1,480
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100 μL
¥ 2,485
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产品介绍

生物活性
产品描述
Anti-Phospho-p70 S6 Kinase (Ser 411) Antibody (7V681) is a Mouse antibody targeting Phospho-p70 S6 Kinase (Ser 411). Anti-Phospho-p70 S6 Kinase (Ser 411) Antibody (7V681) can be used in WB,IP,IF,IHC-P.
别名p-p70 S6 Kinase (Ser 411), p-p70 S6 Kinase (S 411), p70 S6 Kinase (p-Ser 411), p70 S6 Kinase (p-S 411)
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of p70 S6 kinase α phosphorylation in untreated (A,D), insulin treated (B,E) and insulin treated and lambda protein phosphatase treated (C,F) HEK293 whole cell lysates. Antibodies tested include p-p70 S6 kinase α (A-6) (A,B,C) and p70 S6 kinase α (C-18) (D,E,F).
2. Immunofluorescence staining of anisomycin-treated, methanol-fixed NIH/3T3 cells, showing cytoplasmic and nuclear localization of activated p70 S6 kinase α (A). Immunoperoxidase staining of formalin fixed, paraffin-embedded human esophagus tissue showing nuclear staining of squamous epithelial cells (B).
应用
WB
IP
IF
IHC-P
推荐剂量
WB: 1:100-1000; IHC-P: 1:50-500; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景In studies to elucidate key regulatory pathways in signal transduction, several protein serine/threonine (Ser/Thr) kinases have been identified. Included among such kinases are two distinct families of 40S ribosomal protein S6 Ser/Thr kinases present in somatic animal cells, designated p70 S6 kinase and p90 Rsk kinase. p90 Rsk kinase is maximally activated within minutes of addition of growth factors or phorbol ester to cultured cells followed by activation of p70 S6 kinase. Both enzymes are regulated by serine/threonine phosphorylation, suggesting that specific kinases may exist upstream in the signaling pathway that regulate these kinases. In fact, evidence suggests that one such family of activating enzymes includes the members of the ERK MAP kinase family. The ERK MAP kinases are, in turn, regulated by phosphorylation at threonine and tyrosine residues by a protein kinase designated MEK.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
A sequence containing Ser 411 phosphorylated p70 S6 kinase α isoform 2 of human origin
抗原种属
human
Uniprot ID
Q9UBS0
化学信息
分子量Theoretical: 70 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

pp70 S6 Kinase (Ser 411)pp70 S6 Kinase (S 411)p70 S6 Kinase (pSer 411)p70 S6 Kinase (pS 411)p70 S6 Kinase (phospho-Ser 411)p70 S6 Kinase (phospho-S 411)

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