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TIM-1/KIM-1/HAVCR1 Protein, Cynomolgus, Recombinant (His)

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TIM-1/KIM-1/HAVCR1 Protein, Cynomolgus, Recombinant (His)

产品编号 TMPK-00546

Kidney injury molecule 1 (KIM-1, also known as TIM-1) is markedly upregulated in the proximal tubule after injury and is maladaptive when chronically expressed. KIM-1-mediated epithelial cell phagocytosis of apoptotic cells protects the kidney after acute injury by downregulating innate immunity and inflammation. TIM-1/KIM-1/HAVCR1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 35.25 kDa and the accession number is A0A2K5WXJ6.

TIM-1/KIM-1/HAVCR1 Protein, Cynomolgus, Recombinant (His)

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产品编号 TMPK-00546

规格	价格	库存
5 μg	¥ 358	6-8日内发货
10 μg	¥ 573	6-8日内发货
20 μg	¥ 938	5日内发货
50 μg	¥ 1,830	5日内发货
100 μg	¥ 3,100	5日内发货
200 μg	¥ 5,620	5日内发货
500 μg	¥ 12,400	5日内发货

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产品信息

生物活性	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
产品描述	Kidney injury molecule 1 (KIM-1, also known as TIM-1) is markedly upregulated in the proximal tubule after injury and is maladaptive when chronically expressed. KIM-1-mediated epithelial cell phagocytosis of apoptotic cells protects the kidney after acute injury by downregulating innate immunity and inflammation. TIM-1/KIM-1/HAVCR1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 35.25 kDa and the accession number is A0A2K5WXJ6.
种属	Cynomolgus
表达系统	HEK293 Cells
标签	C-His
蛋白编号	A0A2K5WXJ6
别名	TIMD-1,TIMD1,TIM-1,TIM1,TIM,KIM-1,KIM1,HAVcr-1,HAVCR1,HAVCR,CD365
蛋白构建	Val23-Gly342
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量	35.25 kDa (predicted). Due to glycosylation, the protein migrates to 100-150 kDa based on Tris-Bis PAGE result.
内毒素	< 1 EU/μg by the LAL method.
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	Kidney injury molecule 1 (KIM-1, also known as TIM-1) is markedly upregulated in the proximal tubule after injury and is maladaptive when chronically expressed. KIM-1-mediated epithelial cell phagocytosis of apoptotic cells protects the kidney after acute injury by downregulating innate immunity and inflammation.