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顶部生物活性储存和溶解信息计算器

Anti-ABCB1 Antibody (8E719)

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Anti-ABCB1 Antibody (8E719)
产品编号 TMAC-02513
别名 PGY1, P gp, P glycoprotein 1, Multidrug resistance protein 1, Multidrug resistance 1, MDR1, GP170, Doxorubicin resistance, Colchicin sensitivity, CLCS, CD243, ATP-binding cassette sub-family B member 1, ATP binding cassette, sub family B(MDR/TAP), member 1, ABCB1, ABC20

Anti-ABCB1 Antibody (8E719) 是一种 Mouse 抗体，靶向 ABCB1。Anti-ABCB1 Antibody (8E719) 可用于 WB,IP,IF。

Anti-ABCB1 Antibody (8E719)

Anti-ABCB1 Antibody (8E719)

Rating icon 还可以
Anti-ABCB1 Antibody (8E719)
产品编号 TMAC-02513 别名 PGY1, P gp, P glycoprotein 1, Multidrug resistance protein 1, Multidrug resistance 1, MDR1, GP170, Doxorubicin resistance, Colchicin sensitivity, CLCS, CD243, ATP-binding cassette sub-family B member 1, ATP binding cassette, sub family B(MDR/TAP), member 1, ABCB1, ABC20

Anti-ABCB1 Antibody (8E719) 是一种 Mouse 抗体，靶向 ABCB1。Anti-ABCB1 Antibody (8E719) 可用于 WB,IP,IF。

规格价格库存数量
50 μL
¥ 1,985
5日内发货
100 μL
¥ 2,985
5日内发货
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产品介绍

生物活性
产品描述
Anti-ABCB1 Antibody (8E719) is a Mouse antibody targeting ABCB1. Anti-ABCB1 Antibody (8E719) can be used in WB,IP,IF.
别名PGY1, P gp, P glycoprotein 1, Multidrug resistance protein 1, Multidrug resistance 1, MDR1, GP170, Doxorubicin resistance, Colchicin sensitivity, CLCS, CD243, ATP-binding cassette sub-family B member 1, ATP binding cassette, sub family B(MDR/TAP), member 1, ABCB1, ABC20
交叉反应
Human,Mouse,Rat
应用
WB
IP
IF
推荐剂量
WB: 1:10-200; IHC: 1:10-200; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Cells selected for resistance to a single cytotoxic drug may become cross-resistant to a broad range of drugs with different structures and cellular targets. This phenomenon is called multiple drug resistance (MDR). The MDR proteins (Mdrs) are members of a highly conserved superfamily of ATP-binding cassette transport proteins. Mdr functions as an energy-dependent efflux pump for structurally diverse agents ranging from ions to peptides. It is implicated in the development of the multiple drug resistance observed in human cancer cells following prolonged chemotherapy. The classic form of MDR is associated with an increase in the Mdr protein, but not all cases of MDR can be attributed to a rise in Mdr levels. Mdr-1 is an apical transmembrane protein that is an integral part of the blood-brain barrier and functions as a drug-transport pump transporting a variety of drugs from the brain back into the blood. In the human population, there are 15 polymorphisms in the Mdr-1 gene.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Mdr of hamster origin
Uniprot ID
P08183
化学信息
分子量Theoretical: 170 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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