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PDGFB Protein, Human, Recombinant (His)

PDGFB Protein, Human, Recombinant (His)

产品编号 TMPY-04644
别名: platelet-derived growth factor beta polypeptide, SSV, c-sis, SIS, PDGF-2, IBGC5, PDGF2, platelet-derived growth factor β polypeptide, 血小板源生长因子

Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 14.3 kDa and the accession number is P01127-2.

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TargetMol
PDGFB Protein, Human, Recombinant (His)
规格 价格/CNY 货期 数量
50 μg ¥ 3,820 现货
1 mg ¥ 22,400 5日内发货
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产品目录号及名称: PDGFB Protein, Human, Recombinant (His) (TMPY-04644)
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生物活性
技术参数
产品性质
生物活性 Measured by its binding ability in a functional ELISA. Immobilized Human PDGF-B His at 2 μg/ml (100 μl/well) can bind Human PDGFRBHis & hFc, the EC50 of Human PDGFRBHis & hFc is 9.0-40.0 ng/mL.

TargetMol Bioactive

产品描述 Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 14.3 kDa and the accession number is P01127-2.
种属 Human
表达系统 P. pastoris (Yeast)
标签 N-His
蛋白编号 P01127-2
别名 platelet-derived growth factor beta polypeptide, SSV, c-sis, SIS, PDGF-2, IBGC5, PDGF2, platelet-derived growth factor β polypeptide, 血小板源生长因子
蛋白构建 Human PDGFB (NP_148937.1) (Ser82-Thr190)
蛋白纯度 > 95 % as determined by SDS-PAGE.

TargetMol

分子量 14.3 kDa (predicted)
内毒素 < 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液 Supplied as sterile PBS, 25% Glycerol, pH 7.4.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

It is recommended to store the product under sterile conditions at -20°C to -80°C. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor.

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Keywords

PDGFB Protein, Human, Recombinant (His) platelet-derived growth factor beta polypeptide SSV c-sis SIS IBGC 5 PDGF-2 IBGC5 PDGF2 PDGF 2 platelet-derived growth factor β polypeptide IBGC-5 血小板源生长因子 platelet-derived growth factor b polypeptide recombinant recombinant-proteins proteins protein

 

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