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Anti-KIF2C Antibody (4R379) 是一种 Rabbit 抗体,靶向 KIF2C。Anti-KIF2C Antibody (4R379) 可用于 WB,ICC/IF,FCM。
Anti-KIF2C Antibody (4R379) 是一种 Rabbit 抗体,靶向 KIF2C。Anti-KIF2C Antibody (4R379) 可用于 WB,ICC/IF,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 795 | 5日内发货 | |
| 50 μL | ¥ 1,385 | 5日内发货 | |
| 100 μL | ¥ 2,490 | 5日内发货 |
| 产品描述 | Anti-KIF2C Antibody (4R379) is a Rabbit antibody targeting KIF2C. Anti-KIF2C Antibody (4R379) can be used in WB,ICC/IF,FCM. |
| Ig Type | IgG |
| 克隆号 | 4R379 |
| 反应种属 | Human |
| 应用 | WBICC/IFFCM |
| 推荐剂量 | WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm > cytoskeleton. Nucleus. Chromosome > centromere. Chromosome > centromere > kinetochore. Associates with the microtubule network at the growing distal tip (the plus-end) of microtubules, probably through interaction with MTUS2/TIP150 and MAPRE1 (By similarity). Centromeric localization requires the presence of BUB1 and SGOL2. |
| 组织特异性 | Expressed at high levels in thymus and testis, at low levels in small intestine, the mucosal lining of colon, and placenta, and at very low levels in spleen and ovary; expression is not detected in prostate, peripheral blood Leukocytes, heart, brain, lung, liver, skeletal muscle, kidney or pancreas. Isoform 2 is testis-specific. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究背景 | In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells.Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis.Plays a role in chromosome congression and is required for the lateral to end-on conversion of the chromosome-microtubule attachment. |
| 免疫原 | A synthesized peptide: human KIF2C |
| 抗原种属 | Human |
| 基因名称 | Kif2c |
| 基因ID | |
| 蛋白名称 | Kinesin-like protein KIF2C |
| Uniprot ID | |
| 功能 | Promotes ATP-dependent removal of tubulin dimers from microtubules. Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis. |
| 分子量 | Theoretical: 81 kDa. Actual: 81 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |