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Anti-VAPB Antibody (1M998)
还可以产品编号 TMAY-01128
Anti-VAPB Antibody (1M998) 是一种 Rabbit 抗体，靶向 VAPB。Anti-VAPB Antibody (1M998) 可用于 IHC-P。
Anti-VAPB Antibody (1M998)
Anti-VAPB Antibody (1M998)
还可以产品编号 TMAY-01128
Anti-VAPB Antibody (1M998) 是一种 Rabbit 抗体，靶向 VAPB。Anti-VAPB Antibody (1M998) 可用于 IHC-P。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-VAPB Antibody (1M998) is a Rabbit antibody targeting VAPB. Anti-VAPB Antibody (1M998) can be used in IHC-P. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 1M998 |
| 交叉反应 | Human |
| 验证活性 | 1. Immunochemical staining of human VAPB in human pancreas with rabbit monoclonal antibody (1:300, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human VAPB in human liver with rabbit monoclonal antibody (1:300, formalin-fixed paraffin embedded sections). 3. Immunochemical staining of human VAPB in human cirrhosis with rabbit monoclonal antibody (1:300, formalin-fixed paraffin embedded sections). 4. Immunochemical staining of human VAPB in human brain with rabbit monoclonal antibody (1:300, formalin-fixed paraffin embedded sections). |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:100-1:500 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human VAPB / VAP-B (rh VAPB / VAP-B; TMPY-02196; O95292-1; Met1-Pro132). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Vesicle-associated membrane protein-associated protein B / C, also known as VAMP-B/VAMP-C, VAMP-associated protein B/C, VAP-B/VAP-C and VAPB, is a single-pass type IV membrane protein that belongs to the VAMP-associated protein (VAP) family. VAPB contains one MSP domain. VAPB may play a role in vesicle trafficking. VAPB forms a heterodimer with VAPA. VAPB interacts with VAMP1 and VAMP2. Defects in VAPB are the cause of amyotrophic lateral sclerosis type 8 ( ALS8 ) which is a familial form of amyotrophic lateral sclerosis, a neurodegenerative disorder affecting upper and lower motor neurons and resulting in fatal paralysis. Defects in VAPB are also a cause of spinal muscular atrophy autosomal dominant Finkel type (SMAF) which is characterized by proximal muscle weakness that begins in the lower limbs and then progresses to upper limbs. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human VAPB/VAP-B Protein (TMPY-02196) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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