PVRIG Protein, Cynomolgus, Recombinant (hFc)

PVRIG Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 45-55 KDa and the accession number is A0A2K5WVV8.

规格	价格/CNY		数量
10 μg	￥ 550	5日内发货
50 μg	￥ 1,670	5日内发货
500 μg	￥ 14,200	5日内发货
1 mg	￥ 21,300	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 550

5日内发货

50 μg

￥ 1,670

5日内发货

500 μg

￥ 14,200

5日内发货

1 mg

￥ 21,300

5日内发货

产品描述	PVRIG Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 45-55 KDa and the accession number is A0A2K5WVV8.

种属	Cynomolgus
表达系统	HEK293 Cells
标签	C-hFc
蛋白编号	A0A2K5WVV8
别名	C7orf15MGC138295, MGC138297, CD112R, MGC104322, transmembrane protein PVRIG, MGC2463, C7orf15, PVRIG
氨基酸序列	Thr41-Asp171
蛋白构建	Thr41-Asp171
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	45-55 KDa (reducing condition)

内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The extracellular domain sequence of human and mouse PVRIG have approximately 65% similarity. PVRIG functions as a cell surface receptor for Nectin-2/CD112, a cell surface protein that is widely expressed on antigen-presenting cells and tumor cells. Disrupting the PVRIG/Nectin-2 interaction enhances human T cell response, suggesting PVRIG is a novel checkpoint for human T cells. PVRIG may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.

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PVRIG Protein, Cynomolgus, Recombinant (hFc)

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