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顶部生物活性储存和溶解信息计算器

Anti-Profilin-1 Antibody (1I976)

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产品编号 TMAC-03430

别名 Profilin-1, Profilin I, PFN1, Epididymis tissue protein Li 184a

Anti-Profilin-1 Antibody (1I976) 是一种 Rabbit 抗体，靶向 Profilin-1。Anti-Profilin-1 Antibody (1I976) 可用于 FCM,ICC,IHC,WB。

Anti-Profilin-1 Antibody (1I976)

Anti-Profilin-1 Antibody (1I976)

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Rating icon 还可以
产品编号 TMAC-03430 别名 Profilin-1, Profilin I, PFN1, Epididymis tissue protein Li 184a

Anti-Profilin-1 Antibody (1I976) 是一种 Rabbit 抗体，靶向 Profilin-1。Anti-Profilin-1 Antibody (1I976) 可用于 FCM,ICC,IHC,WB。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-Profilin-1 Antibody (1I976) is a Rabbit antibody targeting Profilin-1. Anti-Profilin-1 Antibody (1I976) can be used in FCM,ICC,IHC,WB.
别名Profilin-1, Profilin I, PFN1, Epididymis tissue protein Li 184a
Ig Type
IgG
克隆号
1I976
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of Profilin 1 on Hela cell using anti-Profilin 1 antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Profilin 1 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-Profilin 1 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-Profilin 1 antibody. Counter stained with hematoxylin.
5. ICC staining Profilin 1 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
6. ICC staining Profilin 1 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
7. ICC staining Profilin 1 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
8. Flow cytometric analysis of Hela cells with Profilin 1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
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应用FCMICCIHCWB
推荐剂量
WB: 1:500-2000; IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Profilins regulate Actin polymerization by binding to and sequestering the Actin monomer. Profilins act as a nucleotide exchange factor that charges Actin with ATP after binding the Actin monomer through a 1:1 stoichiometric relationship. Human Profilin-1 and Profilin-2 are encoded by two separate genes mapping to chromosomes 17p13.2 and 3q25.1, respectively. Both Profilin-1 and Profilin-2 are abundantly expressed in kidney. Profilin-1 is highly expressed in lung, liver, placenta and kidney while Profilin-2 is highly expressed in brain and skeletal muscle. In axonal and dendritic processes of mouse brain, Profilins co-localize with dynamin I and synapsin. Profilin may play a role in mediating cell adhesion. The overexpression of Profilin in endothelial cells results in increased adhesion to Fibronectin. In food allergy, plant Profilin is considered a pan-allergen. Case studies indicate individuals with allergies to various foods including celery, carrots, zucchini and peanuts are actually sensitive to the Profilin proteins in these foods.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P07737
化学信息
分子量Theoretical: 15 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

ProfilinIProfilin1PFN 1

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