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Anti-CALML5 Antibody (4X239)

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Anti-CALML5 Antibody (4X239)
产品编号 TMAY-02055
别名 CLSP, calmodulin like 5

Anti-CALML5 Antibody (4X239) 是一种 Rabbit 抗体,靶向 CALML5。Anti-CALML5 Antibody (4X239) 可用于 IHC-P。

Anti-CALML5 Antibody (4X239)
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Anti-CALML5 Antibody (4X239)

Rating icon 还可以
Anti-CALML5 Antibody (4X239)
产品编号 TMAY-02055 别名 CLSP, calmodulin like 5

Anti-CALML5 Antibody (4X239) 是一种 Rabbit 抗体,靶向 CALML5。Anti-CALML5 Antibody (4X239) 可用于 IHC-P。

规格价格库存数量
100 μL
¥ 2,289
5日内发货
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产品介绍

生物活性
产品描述
Anti-CALML5 Antibody (4X239) is a Rabbit antibody targeting CALML5. Anti-CALML5 Antibody (4X239) can be used in IHC-P.
别名CLSP, calmodulin like 5
Ig Type
Rabbit IgG
克隆号
4X239
交叉反应
Human
验证活性
Immunochemical staining of human CALML5 in human skin with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to epithelium.
应用
IHC-P
推荐剂量
IHC-P: 1:100-1:500
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human CALML5 (rh CALML5; TMPY-01953; AAH39172.1; Met1-Glu146).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Calmodulin-like protein 5, also known as Calmodulin-like skin protein, CALML5 and CLSP, is a protein which contains fourEF-hand domains. CALML5 / CLSP is particularly abundant in the epidermis where its expression is directly related to keratinocyte differentiation.The expression is very low in lung. CALML5 / CLSP binds calcium. It may be involved in terminal differentiation of keratinocytes. Coxsackievirus and adenovirus receptor (CAR) is a member of the immunoglobulin (Ig) superfamily and a component of epithelial tight junction. CAR functions as a primary receptor for coxsackievirus B and adenovirus (Ad) infection. CALML5 / CLSP is closely related to CAR. The structure and dynamics of human calmodulin-like skin protein CALML5 / CLSP have been characterized by NMR spectroscopy. The mobility of CALML5 / CLSP has been found to be different for the N-terminal and C-terminal domains. The N-terminal domain is characterized by four stable helices, which experience large fluctuations. This is shown to be due to mutations in the hydrophobic core. The overall N-terminal domain behavior is similar both in the full-length protein and in the isolated domain.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human CALML5 protein (TMPY-01953)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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