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Virstatin

Name: Virstatin
Brand: TargetMol
SKU: T50031
Price: 147 CNY
Availability: InStock
Rating: 5 (10 reviews)

一键复制产品信息

很棒

纯度: 99.94%

货号 T50031Cas号 88909-96-0

Virstatin是一种新型抗病毒药物，是一种有效的病毒复制抑制剂，已被证明对多种病毒有效，包括单纯疱疹病毒（HSV）、人类免疫缺陷病毒（HIV）和流感病毒等。

为众多的药物研发团队赋能，

让新药发现更简单！

Virstatin

一键复制产品信息

很棒

纯度: 99.94%

货号 T50031Cas号 88909-96-0

规格	价格	库存
1 mg	¥ 147	现货
5 mg	¥ 313	现货
10 mg	¥ 455	现货
25 mg	¥ 787	现货
50 mg	¥ 1,090	现货
100 mg	¥ 1,620	现货
500 mg	¥ 3,920	现货

库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单

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TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂

常见问题解答

选择批次:

纯度: 99.94%

颜色: 白色

性状: Solid

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资源下载:

COA HNMR LCMS 产品操作手册

产品介绍

Virstatin AI Summary

Virstatin is a versatile bioactive molecule that targets various biological processes and pathogens. In the context of Vibrio cholerae O395deltalacZ, it inhibits ToxT-mediated transcriptional activation of multiple promoters (tcpA, acfD, ctxAB, tagA, tcpI, acfA, aldA) with an average inhibitory activity ranging from 3.0% to 15.0% at a concentration of 100 µM. Additionally, Virstatin shows inhibition of sodium fluorescein uptake in OATP1B3 and OATP1B1-transfected CHO cells, with inhibition rates of 112.71% and 113.05% at 10 µM, respectively, indicating potential as an OATP1B3 and OATP1B1 transporter inhibitor. The compound also exhibits a broad spectrum of bioactivities, including the inhibition of Menin-MLL interactions in leukemia, Chronic Active B-Cell Receptor Signaling, ELG1-dependent DNA repair, malarial parasite plastid, HP1-beta Chromodomain interactions, and Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1). It also demonstrates synthetic lethality in tumor cells producing 2HG and inhibits MBNL1-poly(CUG) RNA binding. In the context of antiviral activity, Virstatin has shown to inhibit cytotoxicity induced by SARS-CoV-2 in various cell lines, such as Caco-2 and VERO-6 cells, at a concentration of 10 µM. It also inhibits the SARS-CoV-2 3CL-Pro protease at 20 µM with an inhibition rate of 11.36%, and has shown activity against the SARS-CoV-2 (USA-WA1/2020 strain) in HRCE cells. Furthermore, Virstatin demonstrates inhibitory effects against human HDAC6, although with relatively low inhibition percentages of -3.55% and -1.41% using different peptide substrates. Overall, the compound displays a diverse range of bioactivities with potential therapeutic implications in infectious diseases, cancer, and other conditions related to its numerous targets..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Virstatin is a novel antiviral drug that is a potent inhibitor of viral replication and has been shown to be effective against a wide range of viruses, including herpes simplex virus (HSV), human immunodeficiency virus (HIV) and influenza virus.

化学信息

分子量	283.2787
分子式	C₁₆H₁₃NO₄
CAS No.	88909-96-0
Smiles	OC(=O)CCCN1C(=O)C2=CC=CC3=CC=CC(C1=O)=C23
密度	1.403g/cm3

储存&溶解度

存储

溶解度信息

DMSO: 50 mg/mL (176.5 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5301 mL	17.6505 mL	35.3009 mL	176.5046 mL
5 mM	0.7060 mL	3.5301 mL	7.0602 mL	35.3009 mL
10 mM	0.3530 mL	1.7650 mL	3.5301 mL	17.6505 mL
20 mM	0.1765 mL	0.8825 mL	1.7650 mL	8.8252 mL
50 mM	0.0706 mL	0.3530 mL	0.7060 mL	3.5301 mL
100 mM	0.0353 mL	0.1765 mL	0.3530 mL	1.7650 mL

计算器

摩尔浓度计算器
稀释计算器
配液计算器
分子量计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH₂O，那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 100 μL DMSO （母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。