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Anti-GSTA1 Polyclonal Antibody

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货号 TMAB-06822

Anti-GSTA1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 GSTA1。Anti-GSTA1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-GSTA1 Polyclonal Antibody

Anti-GSTA1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-06822

Anti-GSTA1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 GSTA1。Anti-GSTA1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-GSTA1 Polyclonal Antibody is a Rabbit antibody targeting GSTA1. Anti-GSTA1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Dog,Horse,Rabbit)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
组织特异性Liver.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Members of the glutathione S-transferase (GST) family of proteins function in the detoxification of xenobiotics to protect cells against toxicant-induced damage. GSTs are differentially expressed in lung, liver and kidney tissue. Three isoforms, GSTA1-1, GSTA1-4 and GSTM1, localize to the mitochondria in addition to the cytoplasm. In normal and transformed cells, the oncoprotein Myb transcriptionally upregulates GSTM1. This isoform shows high specific activity for aflatoxin B1 epoxide conjugation, suggesting an important role for this interaction in the defense against both chemical and oxidative stress. The C-terminal domain of GSTA1 may form a component of the hydrophobic substrate-binding site, but in contrast appears not to be directly involved in GSH binding and is not absolutely essential for catalytic activity.
抗原信息
免疫原
KLH conjugated synthetic peptide: human GSTA1/Glutathione S Transferase alpha
抗原种属
Human
基因名称
GSTA1
基因ID
蛋白名称
Glutathione S-transferase A1
Uniprot ID
功能
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
化学信息
分子量Theoretical: 25 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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