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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-ASZ1 Polyclonal Antibody

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货号 TMAB-02884

Anti-ASZ1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ASZ1。Anti-ASZ1 Polyclonal Antibody 可用于 WB。

Anti-ASZ1 Polyclonal Antibody

Anti-ASZ1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-02884

Anti-ASZ1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ASZ1。Anti-ASZ1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-ASZ1 Polyclonal Antibody is a Rabbit antibody targeting ASZ1. Anti-ASZ1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Horse)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm (By similarity). Note=Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon during meiosis. Specifically localizes to pi-bodies, a subset of the nuage which contains primary piRNAs (By similarity).
组织特异性Expressed exclusively in the testis and ovary and at higher levels in the adult testis compared with the adult ovary.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景ASZ1 (ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1), also known as ANKL1, ALP1 (Ankyrin-like protein 1), GASZ (germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) or Orf3, is a 475 amino acid protein that is suggested to function as a signal transducer during germ cell maturation. Localized to the cytoplasm of pachytene spermatocytes, early spermatids and oocytes, ASZ1 is primarily found in adult testis and ovary where it mediates protein-protein interactions. ASZ1 contains six ANK repeats, one SAM (sterile alpha motif) domain and is encoded by a gene located on human chromosome 7q31, a region that may have an important role in the development certain types of human cancer.
抗原信息
免疫原
KLH conjugated synthetic peptide: human ASZ1
抗原种属
Human
基因名称
ASZ1
基因ID
136991
蛋白名称
Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1
Uniprot ID
Q8WWH4
功能
Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation (By similarity).
化学信息
分子量Theoretical: 53 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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