- 全部删除
- 您的购物车当前为空
Anti-Phospho-H2AFX (Ser139) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-H2AFX (Ser139)。Anti-Phospho-H2AFX (Ser139) Polyclonal Antibody 可用于 WB,IF。
Anti-Phospho-H2AFX (Ser139) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-H2AFX (Ser139)。Anti-Phospho-H2AFX (Ser139) Polyclonal Antibody 可用于 WB,IF。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,495 | 5日内发货 | |
100 μL | ¥ 2,240 | 5日内发货 |
产品描述 | Anti-Phospho-H2AFX (Ser139) Polyclonal Antibody is a Rabbit antibody targeting Phospho-H2AFX (Ser139). Anti-Phospho-H2AFX (Ser139) Polyclonal Antibody can be used in WB,IF. |
别名 | p-H2AFX (Ser139), p-H2AFX (S139), H2AFX (p-Ser139), H2AFX (p-S139) |
Ig Type | IgG |
交叉反应 | Human |
验证活性 | 1. Western blot analysis of extracts from HT29 cells untreated (lane 1) or treated with UV (lane 2) using Histone H2A.X (Phospho-Ser139) Antibody TMAC-01852. 2. Immunofluorescence staining of methanol-fixed Hela cells using Histone H2A.X (Phospho-Ser139) Antibody TMAC-01852. 3. Western blot analysis of extracts from 293 cells, treated with UV+serum or calf intestinal phosphatase (CIP), using Histone H2A.X (Phospho-Ser139) Antibody TMAC-01852. |
应用 | |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of serine 139 (Q-A-S(p)-Q-E) derived from Human Histone H2AX |
抗原种属 | human |
Uniprot ID |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
评论内容