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Anti-LAMP3/CD208 Antibody (3R433)
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产品编号 TMAY-00947
别名 lysosomal associated membrane protein 3, LAMP3
Anti-LAMP3/CD208 Antibody (3R433) 是一种 Rabbit 抗体，靶向 LAMP3/CD208。Anti-LAMP3/CD208 Antibody (3R433) 可用于 ICC/IF。
Anti-LAMP3/CD208 Antibody (3R433)
Anti-LAMP3/CD208 Antibody (3R433)
还可以产品编号 TMAY-00947 别名 lysosomal associated membrane protein 3, LAMP3
Anti-LAMP3/CD208 Antibody (3R433) 是一种 Rabbit 抗体，靶向 LAMP3/CD208。Anti-LAMP3/CD208 Antibody (3R433) 可用于 ICC/IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 20 μL | ¥ 795 | 5日内发货 | |
| 100 μL | ¥ 2,289 | 5日内发货 |
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抗原信息
| 产品描述 | Anti-LAMP3/CD208 Antibody (3R433) is a Rabbit antibody targeting LAMP3/CD208. Anti-LAMP3/CD208 Antibody (3R433) can be used in ICC/IF. |
| 别名 | lysosomal associated membrane protein 3, LAMP3 |
| Ig Type | Rabbit IgG |
| 克隆号 | 3R433 |
| 交叉反应 | Human |
| 验证活性 | Immunofluorescence staining of Human LAMP3 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human LAMP3 monoclonal antibody (1:60) at 37°C 1 hour. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and countstained with DAPI (blue). Positive staining was localized to cytoplasm. |
| 应用 | |
| 推荐剂量 | ICC-IF: 1:20-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD208 / DC-LAMP / LAMP3 (rh CD208 / DC-LAMP / LAMP3; TMPY-01013; NP_055213.2; Lys28-Thr381). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Dendritic cell-lysosomal associated membrane protein (DC-LAMP)/CD208, also known as LAMP3, is a member of the lysosomal associated membrane protein (LAMP) family, which is specifically expressed by human dendritic cells (DCs) upon activation and therefore serves as a marker of human DC maturation. Confocal and immunoelectron microscopy showed that mouse DC-LAMP protein co-localizes with lbm180, a specific marker for the limiting membrane of lamellar bodies that contain surfactant protein B. The present study demonstrates that DC-LAMP is constitutively expressed by mouse, sheep, and human type II pneumocytes. DC-LAMP is constitutively expressed in normal type II pneumocytes. DC-LAMP is detected first in the activated human DC within MHC class II molecules-containing compartments just before the translocation of MHC class II-peptide complexes to the cell surface, suggesting a possible involvement in this process. Furthermore, overexpression of LAMP3 is actively involved in tumor invasion through increased migration into lymph-vascular spaces. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human CD208 / DC-LAMP / LAMP3 protein (TMPY-01013) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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