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顶部生物活性储存和溶解信息计算器

Anti-LAMP3/CD208 Antibody (3R433)

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产品编号 TMAY-00947

别名 lysosomal associated membrane protein 3, LAMP3

Anti-LAMP3/CD208 Antibody (3R433) 是一种 Rabbit 抗体，靶向 LAMP3/CD208。Anti-LAMP3/CD208 Antibody (3R433) 可用于 ICC/IF。

Anti-LAMP3/CD208 Antibody (3R433)

Anti-LAMP3/CD208 Antibody (3R433)

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Rating icon 还可以
产品编号 TMAY-00947 别名 lysosomal associated membrane protein 3, LAMP3

Anti-LAMP3/CD208 Antibody (3R433) 是一种 Rabbit 抗体，靶向 LAMP3/CD208。Anti-LAMP3/CD208 Antibody (3R433) 可用于 ICC/IF。

规格价格库存数量
20 μL
¥ 795
5日内发货
100 μL
¥ 2,289
5日内发货
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产品介绍

生物活性
产品描述
Anti-LAMP3/CD208 Antibody (3R433) is a Rabbit antibody targeting LAMP3/CD208. Anti-LAMP3/CD208 Antibody (3R433) can be used in ICC/IF.
别名lysosomal associated membrane protein 3, LAMP3
Ig Type
Rabbit IgG
克隆号
3R433
交叉反应
Human
特异性
Human LAMP3/CD208
验证活性
Immunofluorescence staining of Human LAMP3 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human LAMP3 monoclonal antibody (1:60) at 37°C 1 hour. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and countstained with DAPI (blue). Positive staining was localized to cytoplasm.
应用ICC/IF
推荐剂量
ICC-IF: 1:20-1:100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human CD208 / DC-LAMP / LAMP3 (rh CD208 / DC-LAMP / LAMP3; TMPY-01013; NP_055213.2; Lys28-Thr381).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Dendritic cell-lysosomal associated membrane protein (DC-LAMP)/CD208, also known as LAMP3, is a member of the lysosomal associated membrane protein (LAMP) family, which is specifically expressed by human dendritic cells (DCs) upon activation and therefore serves as a marker of human DC maturation. Confocal and immunoelectron microscopy showed that mouse DC-LAMP protein co-localizes with lbm180, a specific marker for the limiting membrane of lamellar bodies that contain surfactant protein B. The present study demonstrates that DC-LAMP is constitutively expressed by mouse, sheep, and human type II pneumocytes. DC-LAMP is constitutively expressed in normal type II pneumocytes. DC-LAMP is detected first in the activated human DC within MHC class II molecules-containing compartments just before the translocation of MHC class II-peptide complexes to the cell surface, suggesting a possible involvement in this process. Furthermore, overexpression of LAMP3 is actively involved in tumor invasion through increased migration into lymph-vascular spaces.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human CD208 / DC-LAMP / LAMP3 protein (TMPY-01013)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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关键词

LAMP-3LAMP 3

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