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Anti-WNK1 Antibody (1S306)
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产品编号 TMAC-04286
别名 WNK 1, Serine/threonine-protein kinase WNK1, Protein kinase with no lysine 1, Protein kinase lysine-deficient 1, PRKWNK1, p65, Kinase deficient protein, KIAA0344, KDP, hWNK1, HSN2, Erythrocyte 65 kDa protein, EC 2.7.11.1
Anti-WNK1 Antibody (1S306) 是一种 Rabbit 抗体，靶向 WNK1。Anti-WNK1 Antibody (1S306) 可用于 WB,IHC。
Anti-WNK1 Antibody (1S306)
Anti-WNK1 Antibody (1S306)
还可以产品编号 TMAC-04286 别名 WNK 1, Serine/threonine-protein kinase WNK1, Protein kinase with no lysine 1, Protein kinase lysine-deficient 1, PRKWNK1, p65, Kinase deficient protein, KIAA0344, KDP, hWNK1, HSN2, Erythrocyte 65 kDa protein, EC 2.7.11.1
Anti-WNK1 Antibody (1S306) 是一种 Rabbit 抗体，靶向 WNK1。Anti-WNK1 Antibody (1S306) 可用于 WB,IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,480 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
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产品介绍
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抗原信息
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| 产品描述 | Anti-WNK1 Antibody (1S306) is a Rabbit antibody targeting WNK1. Anti-WNK1 Antibody (1S306) can be used in WB,IHC. |
| 别名 | WNK 1, Serine/threonine-protein kinase WNK1, Protein kinase with no lysine 1, Protein kinase lysine-deficient 1, PRKWNK1, p65, Kinase deficient protein, KIAA0344, KDP, hWNK1, HSN2, Erythrocyte 65 kDa protein, EC 2.7.11.1 |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of WNK1 on A549 cell lysates using anti-WNK1 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human skin tissue using anti-WNK1 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using anti-WNK1 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-WNK1 antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded rat kidney tissue using anti-WNK1 antibody. Counter stained with hematoxylin. |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000; IHC: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D and SGK1. Controls sodium and chloride ion transport by inhibiting the activity of WNK4, by either phosphorylating the kinase or via an interaction between WNK4 and the autoinhibitory domain of WNK1. WNK4 regulates the activity of the thiazide-sensitive Na-Cl cotransporter, SLC12A3, by phosphorylation. WNK1 may also play a role in actin cytoskeletal reorganization. Phosphorylates NEDD4L. Acts as a scaffold to inhibit SLC4A4, SLC26A6 as well as CFTR activities and surface expression, recruits STK39 which mediates the inhibition. |
| 偶联 | Unconjugated |
| 免疫原 | A synthesized peptide: within Human WNK1 aa 100-200 (Cysteine residue) |
| 抗原种属 | human |
| Uniprot ID |
| 分子量 | Theoretical: 250/300 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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