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Anti-CAMK2 beta Antibody (7C496) 是一种 Mouse 抗体,靶向 CAMK2 beta。Anti-CAMK2 beta Antibody (7C496) 可用于 WB,IHC-P,IHC-Fr,IF。
Anti-CAMK2 beta Antibody (7C496) 是一种 Mouse 抗体,靶向 CAMK2 beta。Anti-CAMK2 beta Antibody (7C496) 可用于 WB,IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 |
| 产品描述 | Anti-CAMK2 beta Antibody (7C496) is a Mouse antibody targeting CAMK2 beta. Anti-CAMK2 beta Antibody (7C496) can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG1 |
| 克隆号 | 7C496 |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WBIHC-PIHC-FrIF |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 亚细胞定位 | Sarcoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side (Probable). |
| 组织特异性 | Expressed in skeletal muscle. |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Protein G purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The multifunctional CaMKII beta, or Ca2+/calmodulin-dependent protein kinase II, is a well known effector of calcium- and calmodulin- mediated functions. It is present in many tissues but is most abundant in the brain. CaMKII is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Autophosphorylation plays an important role in the regulation of the kinase activity. CaMKII is required for synaptic plasticity, as in Long Term Potentiation (LTP), a cellular model for learning and memory. |
| 免疫原 | Recombinant Protein: human CAMK2 between 1-503 amino acids |
| 抗原种属 | Human |
| 基因名称 | CAMK2B |
| 基因ID | |
| 蛋白名称 | Calcium/calmodulin-dependent protein kinase type II subunit beta |
| Uniprot ID | |
| 功能 | Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in sarcoplamic reticulum Ca(2+) transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow-twitch muscles, is involved in regulation of sarcoplamic reticulum (SR) Ca(2+) transport and in fast-twitch muscle participates in the control of Ca(2+) release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In neurons, may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning. |
| 分子量 | Theoretical: 61 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |