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Anti-CAMK2 beta Antibody (7C496)

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货号 TMAB-03590

Anti-CAMK2 beta Antibody (7C496) 是一种 Mouse 抗体,靶向 CAMK2 beta。Anti-CAMK2 beta Antibody (7C496) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-CAMK2 beta Antibody (7C496)

Anti-CAMK2 beta Antibody (7C496)

一键复制产品信息
Rating icon 还可以
货号 TMAB-03590

Anti-CAMK2 beta Antibody (7C496) 是一种 Mouse 抗体,靶向 CAMK2 beta。Anti-CAMK2 beta Antibody (7C496) 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
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产品介绍


生物活性
产品描述
Anti-CAMK2 beta Antibody (7C496) is a Mouse antibody targeting CAMK2 beta. Anti-CAMK2 beta Antibody (7C496) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG1
克隆号
7C496
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Sarcoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side (Probable).
组织特异性Expressed in skeletal muscle.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The multifunctional CaMKII beta, or Ca2+/calmodulin-dependent protein kinase II, is a well known effector of calcium- and calmodulin- mediated functions. It is present in many tissues but is most abundant in the brain. CaMKII is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Autophosphorylation plays an important role in the regulation of the kinase activity. CaMKII is required for synaptic plasticity, as in Long Term Potentiation (LTP), a cellular model for learning and memory.
抗原信息
免疫原
Recombinant Protein: human CAMK2 between 1-503 amino acids
抗原种属
Human
基因名称
CAMK2B
基因ID
蛋白名称
Calcium/calmodulin-dependent protein kinase type II subunit beta
Uniprot ID
功能
Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in sarcoplamic reticulum Ca(2+) transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow-twitch muscles, is involved in regulation of sarcoplamic reticulum (SR) Ca(2+) transport and in fast-twitch muscle participates in the control of Ca(2+) release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In neurons, may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning.
化学信息
分子量Theoretical: 61 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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