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Anti-p63 Antibody (4X27)
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产品编号 TMAC-03013
别名 tumor protein p63, TP73L, TP53L, TP53CP, SHFM4, RHS, p73L, p73H, p63, p53CP, p51, p40, OFC8, NBP, LMS, KET, EEC3, B(p51B), B(p51A), AIS
Anti-p63 Antibody (4X27) 是一种 Rabbit 抗体，靶向 p63。Anti-p63 Antibody (4X27) 可用于 WB,ICC/IF,IHC,FCM。
Anti-p63 Antibody (4X27)
Anti-p63 Antibody (4X27)
还可以产品编号 TMAC-03013 别名 tumor protein p63, TP73L, TP53L, TP53CP, SHFM4, RHS, p73L, p73H, p63, p53CP, p51, p40, OFC8, NBP, LMS, KET, EEC3, B(p51B), B(p51A), AIS
Anti-p63 Antibody (4X27) 是一种 Rabbit 抗体，靶向 p63。Anti-p63 Antibody (4X27) 可用于 WB,ICC/IF,IHC,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,480 | 5日内发货 | |
| 100 μL | ¥ 2,485 | 5日内发货 |
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产品介绍
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抗原信息
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| 产品描述 | Anti-p63 Antibody (4X27) is a Rabbit antibody targeting p63. Anti-p63 Antibody (4X27) can be used in WB,ICC/IF,IHC,FCM. |
| 别名 | tumor protein p63, TP73L, TP53L, TP53CP, SHFM4, RHS, p73L, p73H, p63, p53CP, p51, p40, OFC8, NBP, LMS, KET, EEC3, B(p51B), B(p51A), AIS |
| Ig Type | IgG |
| 克隆号 | 4X27 |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of p63 on human kidney lysates using anti-p63 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-p63 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded mouse prostate tissue using anti-p63 antibody. Counter stained with hematoxylin. 4. ICC staining p63 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. Flow cytometric analysis of A431 cells with p63 antibody at 1/50 dilution (black) compared with an unlabelled control (cells without incubation with primary antibody; red). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. |
| 应用 | |
| 推荐剂量 | WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | The p53 tumor suppressor protein plays a major role in cellular response to DNA damage and other genomic aberrations. Activation of p53 can lead to either cell cycle arrest and DNA repair or apoptosis. In addition to p53, mammalian cells contain two p53 family members, p63 and p73, which are similar to p53 in both structure and function. While p63 can induce p53-responsive genes and apoptosis, mutation of p63 rarely results in tumors. Research investigators frequently observe amplification of the p63 gene in squamous cell carcinomas of the lung, head and neck. The p63 gene contains an alternative transcription initiation site that yields a 40 kDa δNp63 lacking the transactivation domain, and alternative splicing at the carboxy-terminus yields the α, β, and γ isoforms. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 55 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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