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Anti-Phospho-MEF2D (Ser444) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-MEF2D (Ser444)。Anti-Phospho-MEF2D (Ser444) Polyclonal Antibody 可用于 WB,FCM。
Anti-Phospho-MEF2D (Ser444) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-MEF2D (Ser444)。Anti-Phospho-MEF2D (Ser444) Polyclonal Antibody 可用于 WB,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
| 产品描述 | Anti-Phospho-MEF2D (Ser444) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MEF2D (Ser444). Anti-Phospho-MEF2D (Ser444) Polyclonal Antibody can be used in WB,FCM. |
| Ig Type | IgG |
| 反应种属 | Human,Mouse (predicted:Rat,Pig,Cow,Horse,Rabbit) |
| 应用 | WBFCM |
| 推荐剂量 | WB: 1:500-2000; FCM: 0.2μg/Test |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus. Note=Translocated by HDAC4 to nuclear dots. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | MEF2D is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants. |
| 免疫原 | KLH conjugated Synthesised phosphopeptide: human MEF2D around the phosphorylation site of Ser444 |
| 抗原种属 | Human |
| 基因名称 | MEF2D |
| 基因ID | |
| 蛋白名称 | Myocyte-specific enhancer factor 2D |
| Uniprot ID | |
| 功能 | Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific, growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis (By similarity). |
| 分子量 | Theoretical: 56 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |