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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-HENMT1 Polyclonal Antibody

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货号 TMAB-06973

Anti-HENMT1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 HENMT1。Anti-HENMT1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-HENMT1 Polyclonal Antibody

Anti-HENMT1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-06973

Anti-HENMT1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 HENMT1。Anti-HENMT1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

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产品描述
Anti-HENMT1 Polyclonal Antibody is a Rabbit antibody targeting HENMT1. Anti-HENMT1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm (By similarity). Note=Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon during meiosis (By similarity).
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景C1orf59 is a 393 amino acid protein that belongs to the UPF0486 family. C1orf59 is considered a complete proteome and maps to chromosome 1p13.3. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
抗原信息
免疫原
KLH conjugated synthetic peptide: human HENMT1
抗原种属
Human
基因名称
HENMT1
基因ID
113802
蛋白名称
Small RNA 2'-O-methyltransferase
Uniprot ID
Q5T8I9
功能
Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis (By similarity).
化学信息
分子量Theoretical: 45 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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