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Anti-IFI30 Antibody (9J659) 是一种 Mouse 抗体,靶向 IFI30。Anti-IFI30 Antibody (9J659) 可用于 ELISA。
Anti-IFI30 Antibody (9J659) 是一种 Mouse 抗体,靶向 IFI30。Anti-IFI30 Antibody (9J659) 可用于 ELISA。
产品描述 | Anti-IFI30 Antibody (9J659) is a Mouse antibody targeting IFI30. Anti-IFI30 Antibody (9J659) can be used in ELISA. |
Ig Type | Monoclonal Mouse IgG2b |
克隆号 | 9J659 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:1000-1:2000 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This product is a recombinant monoclonal antibody expressed from HEK293 cells. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | IFI30 belongs to the GILT family. This family includes the two characterized human gamma-interferon-inducible lysosomal thiol reductase (GILT) sequences: P13284 and Q9UL08. It also contains several other eukaryotic putative proteins with similarity to GILT. The aligned region contains three conserved cysteine residues. Besides, the two GILT sequences possess a C-X(2)-C motif that is shared by some of the other sequences in the family. This motif is thought to be associated with disulfide bond reduction. IFI30 is a lysosomal thiol reductase that can reduce protein disulfide bonds. It facilitates the generation of MHC class II-restricted epitopes from disulfide bond-containing antigens by the endocytic reduction of disulfide bonds. It also facilitates MHC class I-restricted recognition of exogenous antigens containing disulfide bonds by CD8+ T-cells or cross-presentation. IFI30 may facilitate the complete unfolding of proteins destined for lysosomal degradation and plays an important role in antigen processing. |
偶联 | Unconjugated |
免疫原 | Recombinant Human IFI30 Protein (TMPY-02887) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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