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Anti-KNG1 Antibody (6F800) 是一种 Mouse 抗体,靶向 KNG1。Anti-KNG1 Antibody (6F800) 可用于 ELISA。
Anti-KNG1 Antibody (6F800) 是一种 Mouse 抗体,靶向 KNG1。Anti-KNG1 Antibody (6F800) 可用于 ELISA。
产品描述 | Anti-KNG1 Antibody (6F800) is a Mouse antibody targeting KNG1. Anti-KNG1 Antibody (6F800) can be used in ELISA. |
Ig Type | Monoclonal Mouse IgG2b |
克隆号 | 6F800 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:1000-1:2000 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human KNG1 / Kininogen 1 (rh KNG1 / Kininogen 1; TMPY-01598; NP_001095886.1; Gln 19-Ser 644). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Kininogen-1, also known as high molecular weight kininogen, Williams-Fitzgerald-Flaujeac factor, Alpha-2-thiol proteinase inhibitor, Fitzgerald factor, KNG1, and BDK, is a secreted protein that contains three cystatin domains. Kininogen-1 / KNG1 is a protein from the blood coagulation system as well as the kinin-kallikrein system. It is a protein that adsorbs to the surface of biomaterials that come in contact with blood. Kininogen-1 / KNG1 circulates throughout the blood and quickly adsorbs to the material surfaces. Kininogen-1 / KNG1 is one of the early participants of the intrinsic pathway of coagulation, together with Factor XII (Hageman factor) and prekallikrein. Kininogen-1 / KNG1 is one of the kininogens, a class of proteins. As with many other coagulation proteins, the protein was initially named after the patients in whom deficiency was first observed. When the clinical data were combined, it turned out that all patients had a deficiency of the same protein. Defects in KNG1 are the cause of high molecular weight kininogen deficiency (HMWK deficiency) which is an autosomal recessive coagulation defect. Patients with HWMK deficiency do not have a hemorrhagic tendency, but they exhibit abnormal surface-mediated activation of fibrinolysis. |
偶联 | Unconjugated |
免疫原 | Recombinant Human KNG1 / Kininogen 1 Protein (TMPY-01598) |
抗原种属 | Human |
研究领域 | Neurotransmitter Associated Enzymes |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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