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Anti-FOXK1 Polyclonal Antibody

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货号 TMAB-06128

Anti-FOXK1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FOXK1。Anti-FOXK1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-FOXK1 Polyclonal Antibody

Anti-FOXK1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-06128

Anti-FOXK1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FOXK1。Anti-FOXK1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-FOXK1 Polyclonal Antibody is a Rabbit antibody targeting FOXK1. Anti-FOXK1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Pig,Cow,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Expressed both developing and adult tissues. In adults, significant expression is seen in tumors of the brain, colon and lymph node.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The FOX family of transcription factors share a common DIUA binding domain termed a winged-helix or forkhead domain. Many FOX proteins play important roles in development, metabolism, cancer and aging. In skeletal muscles, undifferentiated myogenic stem cells (satellite cells) can mobilize to regenerate myofibers in response to injury. FOXK1 is expressed in these cells and regulates cell cycle progression through an interaction with its downstream target the cyclin-dependent kinase inhibitor p21 (CIP). Loss of FOXK1 in mice results in growth retardation and a severe impairment in skeletal muscle regeneration following injury. FOXK1 also shows expression in immature tissues of brain, eye, heart, lung and thymus. It also is predominantly expressed in many malignant tissues, such as tumors of the brain, colon and lymph node.
抗原信息
免疫原
KLH conjugated synthetic peptide: human FOXK1
抗原种属
Human
基因名称
FOXK1
基因ID
蛋白名称
Forkhead box protein K1
Uniprot ID
功能
Transcriptional regulator that binds to the upstream enhancer region (CCAC box) of myoglobin gene. Has a role in myogenic differentiation and in remodeling processes of adult muscles that occur in response to physiological stimuli.
化学信息
分子量Theoretical: 75 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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